Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice

BACKGROUND: Tumor immune responses are first generated and metastases often begin in tumor sentinel lymph nodes (TSLN). Therefore, it is important to promote tumor immunity within this microenvironment. Mifepristone (RU486) treatment can interfere with cortisol signaling that can lead to suppression...

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Detalles Bibliográficos
Autores principales: Gabaglia, Claudia Raja, DeLaney, Alexandra, Gee, Jennifer, Halder, Ramesh, Graham, Frank L, Gauldie, Jack, Sercarz, Eli E, Braciak, Todd A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976733/
https://www.ncbi.nlm.nih.gov/pubmed/20946663
http://dx.doi.org/10.1186/1479-5876-8-98

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