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Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate
In the title compound, C(15)H(18)N(2)O(5)·H(2)O, the pyrimidine ring adopts a flattened-boat conformation. The ethoxy group attached to the benzene ring is in an extended conformation. The oxopyrimidine molecules are linked into centrosymmetric R (2) (2)(20) dimers by O—H⋯O hydrogen bonds. The dim...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977098/ https://www.ncbi.nlm.nih.gov/pubmed/21583606 http://dx.doi.org/10.1107/S160053680902769X |
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| author | Thenmozhi, M. Kavitha, T. Satyanarayana, V. S. V. Vijayakumar, V. Ponnuswamy, M. N. |
| author_facet | Thenmozhi, M. Kavitha, T. Satyanarayana, V. S. V. Vijayakumar, V. Ponnuswamy, M. N. |
| author_sort | Thenmozhi, M. |
| collection | PubMed |
| description | In the title compound, C(15)H(18)N(2)O(5)·H(2)O, the pyrimidine ring adopts a flattened-boat conformation. The ethoxy group attached to the benzene ring is in an extended conformation. The oxopyrimidine molecules are linked into centrosymmetric R (2) (2)(20) dimers by O—H⋯O hydrogen bonds. The dimers are linked by N—H⋯O hydrogen bonds, forming a two-dimensional network parallel to the bc plane. Adjacent networks are cross-linked via N—H⋯O and O—H⋯O hydrogen bonds involving the water molecules. |
| format | Text |
| id | pubmed-2977098 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29770982010-12-30 Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate Thenmozhi, M. Kavitha, T. Satyanarayana, V. S. V. Vijayakumar, V. Ponnuswamy, M. N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(18)N(2)O(5)·H(2)O, the pyrimidine ring adopts a flattened-boat conformation. The ethoxy group attached to the benzene ring is in an extended conformation. The oxopyrimidine molecules are linked into centrosymmetric R (2) (2)(20) dimers by O—H⋯O hydrogen bonds. The dimers are linked by N—H⋯O hydrogen bonds, forming a two-dimensional network parallel to the bc plane. Adjacent networks are cross-linked via N—H⋯O and O—H⋯O hydrogen bonds involving the water molecules. International Union of Crystallography 2009-07-18 /pmc/articles/PMC2977098/ /pubmed/21583606 http://dx.doi.org/10.1107/S160053680902769X Text en © Thenmozhi et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Thenmozhi, M. Kavitha, T. Satyanarayana, V. S. V. Vijayakumar, V. Ponnuswamy, M. N. Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title | Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title_full | Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title_fullStr | Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title_full_unstemmed | Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title_short | Methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| title_sort | methyl 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977098/ https://www.ncbi.nlm.nih.gov/pubmed/21583606 http://dx.doi.org/10.1107/S160053680902769X |
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