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1-Chloro­acetyl-2,6-bis­(3-fluoro­phen­yl)piperidin-4-one

In the title compound C(19)H(16)ClF(2)NO(2), the piperidone ring adopts a twist-boat conformation with the two out-of-plane atoms deviating by 0.544 (1) and 0.511 (1) Å from the plane through the remaining atoms in the ring. Sterically favoured non-H-atom C⋯O inter­molecular contacts are observed in...

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Detalles Bibliográficos
Autores principales: Aridoss, G., Gayathri, D., Velmurugan, D., Kim, M. S., Jeong, Yeon Tae
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977122/
https://www.ncbi.nlm.nih.gov/pubmed/21583667
http://dx.doi.org/10.1107/S1600536809028529
Descripción
Sumario:In the title compound C(19)H(16)ClF(2)NO(2), the piperidone ring adopts a twist-boat conformation with the two out-of-plane atoms deviating by 0.544 (1) and 0.511 (1) Å from the plane through the remaining atoms in the ring. Sterically favoured non-H-atom C⋯O inter­molecular contacts are observed in the structure, within a 3.00 Å range. The crystal packing is stabilized by C—H⋯O and C—H⋯F hydrogen bonds and an inter­molecular π–π inter­action [centroid-centroid separation of 3.783 (1) Å]. Alternating C—H⋯O and C—H⋯F inter­molecular inter­actions generate chains running along the a axis, while a centrosymmetric R (2) (2)(16) ring involving C—H⋯O inter­actions is formed centred at (1/2, 1/2, 0).