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Ethyl 1-acetyl-1H-indole-3-carboxyl­ate

The title compound, C(13)H(13)NO(3), was synthesized by acetyl­ation of ethyl 1H-indole-3-carboxyl­ate. The aromatic ring system of the mol­ecule is essentially planar, but the saturated ethyl group is also located within this plane and the overall r.m.s. deviation from planarity is only 0.034 Å. Pa...

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Detalles Bibliográficos
Autores principales: Siddiquee, Tasneem, Islam, Shahid, Bennett, Dennis, Zeller, Matthias, Hossain, Mahmun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977149/
https://www.ncbi.nlm.nih.gov/pubmed/21583507
http://dx.doi.org/10.1107/S1600536809025379
Descripción
Sumario:The title compound, C(13)H(13)NO(3), was synthesized by acetyl­ation of ethyl 1H-indole-3-carboxyl­ate. The aromatic ring system of the mol­ecule is essentially planar, but the saturated ethyl group is also located within this plane and the overall r.m.s. deviation from planarity is only 0.034 Å. Pairs of C—H⋯O inter­actions connect mol­ecules into chains along the diagonal of the unit cell. Mol­ecules also form weakly connected dimers via π⋯π stacking inter­actions of the indole rings with centroid–centroid separations of 3.571 (1) Å. C—H⋯π inter­actions between methyl­ene and methyl groups and the indole and benzene ring complete the directional inter­molecular inter­actions found in the crystal structure.