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tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate

In the mol­ecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, inter­molecular N—H⋯N hydrogen bonds link the mol­ecules into centrosymmetric dimers, f...

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Detalles Bibliográficos
Autores principales: Tang, Shi-Gui, Wang, Jian-Qiang, Guo, Cheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977178/
https://www.ncbi.nlm.nih.gov/pubmed/21583549
http://dx.doi.org/10.1107/S1600536809025604
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author Tang, Shi-Gui
Wang, Jian-Qiang
Guo, Cheng
author_facet Tang, Shi-Gui
Wang, Jian-Qiang
Guo, Cheng
author_sort Tang, Shi-Gui
collection PubMed
description In the mol­ecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, inter­molecular N—H⋯N hydrogen bonds link the mol­ecules into centrosymmetric dimers, forming R (2) (2)(24) ring motifs; the dimers are linked by inter­molecular C—H⋯O hydrogen bonds into a two-dimensional network. π–π contacts between the benzene rings and between the pyrimidine and pyridine rings [centroid–centroid distances = 3.891 (1) and 3.646 (1) Å, respectively] may further stabilize the structure. Two weak C—H⋯π inter­actions are also present.
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spelling pubmed-29771782010-12-30 tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate Tang, Shi-Gui Wang, Jian-Qiang Guo, Cheng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, inter­molecular N—H⋯N hydrogen bonds link the mol­ecules into centrosymmetric dimers, forming R (2) (2)(24) ring motifs; the dimers are linked by inter­molecular C—H⋯O hydrogen bonds into a two-dimensional network. π–π contacts between the benzene rings and between the pyrimidine and pyridine rings [centroid–centroid distances = 3.891 (1) and 3.646 (1) Å, respectively] may further stabilize the structure. Two weak C—H⋯π inter­actions are also present. International Union of Crystallography 2009-07-11 /pmc/articles/PMC2977178/ /pubmed/21583549 http://dx.doi.org/10.1107/S1600536809025604 Text en © Tang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tang, Shi-Gui
Wang, Jian-Qiang
Guo, Cheng
tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title_full tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title_fullStr tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title_full_unstemmed tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title_short tert-Butyl N-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
title_sort tert-butyl n-{4-methyl-3-[4-(3-pyrid­yl)pyrimidin-2-yl­oxy]phen­yl}carbamate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977178/
https://www.ncbi.nlm.nih.gov/pubmed/21583549
http://dx.doi.org/10.1107/S1600536809025604
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