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tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate
In the molecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, intermolecular N—H⋯N hydrogen bonds link the molecules into centrosymmetric dimers, f...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977178/ https://www.ncbi.nlm.nih.gov/pubmed/21583549 http://dx.doi.org/10.1107/S1600536809025604 |
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author | Tang, Shi-Gui Wang, Jian-Qiang Guo, Cheng |
author_facet | Tang, Shi-Gui Wang, Jian-Qiang Guo, Cheng |
author_sort | Tang, Shi-Gui |
collection | PubMed |
description | In the molecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, intermolecular N—H⋯N hydrogen bonds link the molecules into centrosymmetric dimers, forming R (2) (2)(24) ring motifs; the dimers are linked by intermolecular C—H⋯O hydrogen bonds into a two-dimensional network. π–π contacts between the benzene rings and between the pyrimidine and pyridine rings [centroid–centroid distances = 3.891 (1) and 3.646 (1) Å, respectively] may further stabilize the structure. Two weak C—H⋯π interactions are also present. |
format | Text |
id | pubmed-2977178 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29771782010-12-30 tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate Tang, Shi-Gui Wang, Jian-Qiang Guo, Cheng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the molecule of the title compound, C(21)H(22)N(4)O(3), the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, intermolecular N—H⋯N hydrogen bonds link the molecules into centrosymmetric dimers, forming R (2) (2)(24) ring motifs; the dimers are linked by intermolecular C—H⋯O hydrogen bonds into a two-dimensional network. π–π contacts between the benzene rings and between the pyrimidine and pyridine rings [centroid–centroid distances = 3.891 (1) and 3.646 (1) Å, respectively] may further stabilize the structure. Two weak C—H⋯π interactions are also present. International Union of Crystallography 2009-07-11 /pmc/articles/PMC2977178/ /pubmed/21583549 http://dx.doi.org/10.1107/S1600536809025604 Text en © Tang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Tang, Shi-Gui Wang, Jian-Qiang Guo, Cheng tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title |
tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title_full |
tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title_fullStr |
tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title_full_unstemmed |
tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title_short |
tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
title_sort | tert-butyl n-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977178/ https://www.ncbi.nlm.nih.gov/pubmed/21583549 http://dx.doi.org/10.1107/S1600536809025604 |
work_keys_str_mv | AT tangshigui tertbutyln4methyl343pyridylpyrimidin2yloxyphenylcarbamate AT wangjianqiang tertbutyln4methyl343pyridylpyrimidin2yloxyphenylcarbamate AT guocheng tertbutyln4methyl343pyridylpyrimidin2yloxyphenylcarbamate |