1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid

The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo­propyl-6-fluoro-4-oxo-7-(1-piperazin­yl)-1,4-dihydro­quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds together with π–π electron ring inter­actions [centroid–cent...

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Detalles Bibliográficos
Autores principales: Li, Tao, Tang, Li-Rong, Zeng, Qiao-Ling, Chen, Wei-Jin, Huang, Biao
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977261/
https://www.ncbi.nlm.nih.gov/pubmed/21583715
http://dx.doi.org/10.1107/S1600536809029729
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author Li, Tao
Tang, Li-Rong
Zeng, Qiao-Ling
Chen, Wei-Jin
Huang, Biao
author_facet Li, Tao
Tang, Li-Rong
Zeng, Qiao-Ling
Chen, Wei-Jin
Huang, Biao
author_sort Li, Tao
collection PubMed
description The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo­propyl-6-fluoro-4-oxo-7-(1-piperazin­yl)-1,4-dihydro­quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds together with π–π electron ring inter­actions [centroid–centroid separations between quinoline rings of 3.5864 (11) and 3.9339 (13) Å]. A strong intra­molecular O—H⋯O hydrogen bonds is present as well as an intra­molecular C—H⋯F inter­action.
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spelling pubmed-29772612010-12-30 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid Li, Tao Tang, Li-Rong Zeng, Qiao-Ling Chen, Wei-Jin Huang, Biao Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(17)H(17)FN(4)O(4), is a derivative of ciprofloxacin [1-cyclo­propyl-6-fluoro-4-oxo-7-(1-piperazin­yl)-1,4-dihydro­quinoline-3-carboxylic acid]. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds together with π–π electron ring inter­actions [centroid–centroid separations between quinoline rings of 3.5864 (11) and 3.9339 (13) Å]. A strong intra­molecular O—H⋯O hydrogen bonds is present as well as an intra­molecular C—H⋯F inter­action. International Union of Crystallography 2009-07-31 /pmc/articles/PMC2977261/ /pubmed/21583715 http://dx.doi.org/10.1107/S1600536809029729 Text en © Li et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Li, Tao
Tang, Li-Rong
Zeng, Qiao-Ling
Chen, Wei-Jin
Huang, Biao
1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title_full 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title_fullStr 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title_full_unstemmed 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title_short 1-Cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
title_sort 1-cyclo­propyl-6-fluoro-7-(4-nitro­so­piperazin-1-yl)-4-oxo-1,4-dihydro­quinoline-3-carboxylic acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977261/
https://www.ncbi.nlm.nih.gov/pubmed/21583715
http://dx.doi.org/10.1107/S1600536809029729
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AT chenweijin 1cyclopropyl6fluoro74nitrosopiperazin1yl4oxo14dihydroquinoline3carboxylicacid
AT huangbiao 1cyclopropyl6fluoro74nitrosopiperazin1yl4oxo14dihydroquinoline3carboxylicacid

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