(4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide

The title compound, C(11)H(11)ClN(2)O(4), is an important inter­mediate for the preparation of platinum anti­cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro­phenyl substituent. In the crystal structure, mol­ecules are linked into a two-dimensional ne...

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Detalles Bibliográficos
Autores principales: Wang, De-Cai, Bai, Jing, Xu, Wei, Gai, Tao, Liu, Hua-Quan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977328/
https://www.ncbi.nlm.nih.gov/pubmed/21583638
http://dx.doi.org/10.1107/S1600536809027494
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author Wang, De-Cai
Bai, Jing
Xu, Wei
Gai, Tao
Liu, Hua-Quan
author_facet Wang, De-Cai
Bai, Jing
Xu, Wei
Gai, Tao
Liu, Hua-Quan
author_sort Wang, De-Cai
collection PubMed
description The title compound, C(11)H(11)ClN(2)O(4), is an important inter­mediate for the preparation of platinum anti­cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro­phenyl substituent. In the crystal structure, mol­ecules are linked into a two-dimensional network parallel to (001) by N—H⋯O and C—H⋯O hydrogen bonds.
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spelling pubmed-29773282010-12-30 (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide Wang, De-Cai Bai, Jing Xu, Wei Gai, Tao Liu, Hua-Quan Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(11)H(11)ClN(2)O(4), is an important inter­mediate for the preparation of platinum anti­cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro­phenyl substituent. In the crystal structure, mol­ecules are linked into a two-dimensional network parallel to (001) by N—H⋯O and C—H⋯O hydrogen bonds. International Union of Crystallography 2009-07-22 /pmc/articles/PMC2977328/ /pubmed/21583638 http://dx.doi.org/10.1107/S1600536809027494 Text en © Wang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, De-Cai
Bai, Jing
Xu, Wei
Gai, Tao
Liu, Hua-Quan
(4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title_full (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title_fullStr (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title_full_unstemmed (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title_short (4S,5S)-2-(4-Chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
title_sort (4s,5s)-2-(4-chloro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977328/
https://www.ncbi.nlm.nih.gov/pubmed/21583638
http://dx.doi.org/10.1107/S1600536809027494
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