N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide

The title compound, C(14)H(14)N(2)O(6)S, is an inter­mediate for the synthesis of β-3-adrenergic receptor agonists. The two meth­oxy groups are approximately coplanar with the attached benzene ring [C—O—C—C = −2.7 (4) and 9.4 (4)°]. The dihedral angle between the two aromatic rings is 67.16 (12)°. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Guo-Yao, Qian, Shan, Li, Xiao-Cen, Wu, Yong
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977360/
https://www.ncbi.nlm.nih.gov/pubmed/21583621
http://dx.doi.org/10.1107/S1600536809027962
_version_ 1782191089427415040
author Zhang, Guo-Yao
Qian, Shan
Li, Xiao-Cen
Wu, Yong
author_facet Zhang, Guo-Yao
Qian, Shan
Li, Xiao-Cen
Wu, Yong
author_sort Zhang, Guo-Yao
collection PubMed
description The title compound, C(14)H(14)N(2)O(6)S, is an inter­mediate for the synthesis of β-3-adrenergic receptor agonists. The two meth­oxy groups are approximately coplanar with the attached benzene ring [C—O—C—C = −2.7 (4) and 9.4 (4)°]. The dihedral angle between the two aromatic rings is 67.16 (12)°. An intra­molecular N—H⋯O hydrogen bond is observed. In the crystal, mol­ecules are linked into chains along the c axis by C—H⋯O hydrogen bonds.
format Text
id pubmed-2977360
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29773602010-12-30 N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide Zhang, Guo-Yao Qian, Shan Li, Xiao-Cen Wu, Yong Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(14)N(2)O(6)S, is an inter­mediate for the synthesis of β-3-adrenergic receptor agonists. The two meth­oxy groups are approximately coplanar with the attached benzene ring [C—O—C—C = −2.7 (4) and 9.4 (4)°]. The dihedral angle between the two aromatic rings is 67.16 (12)°. An intra­molecular N—H⋯O hydrogen bond is observed. In the crystal, mol­ecules are linked into chains along the c axis by C—H⋯O hydrogen bonds. International Union of Crystallography 2009-07-22 /pmc/articles/PMC2977360/ /pubmed/21583621 http://dx.doi.org/10.1107/S1600536809027962 Text en © Zhang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhang, Guo-Yao
Qian, Shan
Li, Xiao-Cen
Wu, Yong
N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title_full N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title_fullStr N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title_full_unstemmed N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title_short N-(2,5-Dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
title_sort n-(2,5-dimethoxy­phen­yl)-4-nitro­benzene­sulfonamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977360/
https://www.ncbi.nlm.nih.gov/pubmed/21583621
http://dx.doi.org/10.1107/S1600536809027962
work_keys_str_mv AT zhangguoyao n25dimethoxyphenyl4nitrobenzenesulfonamide
AT qianshan n25dimethoxyphenyl4nitrobenzenesulfonamide
AT lixiaocen n25dimethoxyphenyl4nitrobenzenesulfonamide
AT wuyong n25dimethoxyphenyl4nitrobenzenesulfonamide

Ejemplares similares