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6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the molecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an intermediate conformation between the chair and boat forms...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977403/ https://www.ncbi.nlm.nih.gov/pubmed/21583484 http://dx.doi.org/10.1107/S160053680902460X |
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author | Okmanov, Rasul Ya. Samarov, Zafir U. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusniddin M. |
author_facet | Okmanov, Rasul Ya. Samarov, Zafir U. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusniddin M. |
author_sort | Okmanov, Rasul Ya. |
collection | PubMed |
description | The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the molecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an intermediate conformation between the chair and boat forms as it is typical for cyclooctene rings. An ethylene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910 (7):0.090 (7). In the crystal, the H atoms of the aromatic rings form weak C—H⋯O and C—H⋯N hydrogen bonds. One C—H⋯O hydrogen bond leads to the formation of a one-dimensional chain. Another C—H⋯O and a C—H⋯N bond link these chains, generating a three-dimensional network. |
format | Text |
id | pubmed-2977403 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29774032010-12-30 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one Okmanov, Rasul Ya. Samarov, Zafir U. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusniddin M. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the molecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an intermediate conformation between the chair and boat forms as it is typical for cyclooctene rings. An ethylene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910 (7):0.090 (7). In the crystal, the H atoms of the aromatic rings form weak C—H⋯O and C—H⋯N hydrogen bonds. One C—H⋯O hydrogen bond leads to the formation of a one-dimensional chain. Another C—H⋯O and a C—H⋯N bond link these chains, generating a three-dimensional network. International Union of Crystallography 2009-07-04 /pmc/articles/PMC2977403/ /pubmed/21583484 http://dx.doi.org/10.1107/S160053680902460X Text en © Okmanov et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Okmanov, Rasul Ya. Samarov, Zafir U. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusniddin M. 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title | 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title_full | 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title_fullStr | 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title_full_unstemmed | 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title_short | 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one |
title_sort | 6,7,8,9,10,11-hexahydro-13h-azocino[2,1-b]quinazolin-13-one |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977403/ https://www.ncbi.nlm.nih.gov/pubmed/21583484 http://dx.doi.org/10.1107/S160053680902460X |
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