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6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one

The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the mol­ecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an inter­mediate conformation between the chair and boat forms...

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Autores principales: Okmanov, Rasul Ya., Samarov, Zafir U., Turgunov, Kambarali K., Tashkhodjaev, Bakhodir, Shakhidoyatov, Khusniddin M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977403/
https://www.ncbi.nlm.nih.gov/pubmed/21583484
http://dx.doi.org/10.1107/S160053680902460X
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author Okmanov, Rasul Ya.
Samarov, Zafir U.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusniddin M.
author_facet Okmanov, Rasul Ya.
Samarov, Zafir U.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusniddin M.
author_sort Okmanov, Rasul Ya.
collection PubMed
description The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the mol­ecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an inter­mediate conformation between the chair and boat forms as it is typical for cyclo­octene rings. An ethyl­ene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910 (7):0.090 (7). In the crystal, the H atoms of the aromatic rings form weak C—H⋯O and C—H⋯N hydrogen bonds. One C—H⋯O hydrogen bond leads to the formation of a one-dimensional chain. Another C—H⋯O and a C—H⋯N bond link these chains, generating a three-dimensional network.
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spelling pubmed-29774032010-12-30 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one Okmanov, Rasul Ya. Samarov, Zafir U. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusniddin M. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(16)N(2)O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the mol­ecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an inter­mediate conformation between the chair and boat forms as it is typical for cyclo­octene rings. An ethyl­ene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910 (7):0.090 (7). In the crystal, the H atoms of the aromatic rings form weak C—H⋯O and C—H⋯N hydrogen bonds. One C—H⋯O hydrogen bond leads to the formation of a one-dimensional chain. Another C—H⋯O and a C—H⋯N bond link these chains, generating a three-dimensional network. International Union of Crystallography 2009-07-04 /pmc/articles/PMC2977403/ /pubmed/21583484 http://dx.doi.org/10.1107/S160053680902460X Text en © Okmanov et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Okmanov, Rasul Ya.
Samarov, Zafir U.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusniddin M.
6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title_full 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title_fullStr 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title_full_unstemmed 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title_short 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one
title_sort 6,7,8,9,10,11-hexahydro-13h-azocino[2,1-b]quinazolin-13-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977403/
https://www.ncbi.nlm.nih.gov/pubmed/21583484
http://dx.doi.org/10.1107/S160053680902460X
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