Abacavir methanol 2.5-solvate

The structure of abacavir (systematic name: {(1S,4R)-4-[2-amino-6-(cyclo­propyl­amino)-9H-purin-9-yl]cyclo­pent-2-en-1-yl}methanol), C(14)H(18)N(6)O·2.5CH(3)OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N ato...

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Autor principal: Pham, Phuong-Truc T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977439/
https://www.ncbi.nlm.nih.gov/pubmed/21583619
http://dx.doi.org/10.1107/S1600536809027743
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author Pham, Phuong-Truc T.
author_facet Pham, Phuong-Truc T.
author_sort Pham, Phuong-Truc T.
collection PubMed
description The structure of abacavir (systematic name: {(1S,4R)-4-[2-amino-6-(cyclo­propyl­amino)-9H-purin-9-yl]cyclo­pent-2-en-1-yl}methanol), C(14)H(18)N(6)O·2.5CH(3)OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N atoms on an adjacent purine. The asymmetric unit also contains 2.5 mol­ecules of methanol solvate which were grossly disordered and were excluded using SQUEEZE subroutine in PLATON [Spek, (2009 ▶). Acta Cryst. D65, 148–155].
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spelling pubmed-29774392010-12-30 Abacavir methanol 2.5-solvate Pham, Phuong-Truc T. Acta Crystallogr Sect E Struct Rep Online Organic Papers The structure of abacavir (systematic name: {(1S,4R)-4-[2-amino-6-(cyclo­propyl­amino)-9H-purin-9-yl]cyclo­pent-2-en-1-yl}methanol), C(14)H(18)N(6)O·2.5CH(3)OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N atoms on an adjacent purine. The asymmetric unit also contains 2.5 mol­ecules of methanol solvate which were grossly disordered and were excluded using SQUEEZE subroutine in PLATON [Spek, (2009 ▶). Acta Cryst. D65, 148–155]. International Union of Crystallography 2009-07-22 /pmc/articles/PMC2977439/ /pubmed/21583619 http://dx.doi.org/10.1107/S1600536809027743 Text en © Phuong-Truc T. Pham 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Pham, Phuong-Truc T.
Abacavir methanol 2.5-solvate
title Abacavir methanol 2.5-solvate
title_full Abacavir methanol 2.5-solvate
title_fullStr Abacavir methanol 2.5-solvate
title_full_unstemmed Abacavir methanol 2.5-solvate
title_short Abacavir methanol 2.5-solvate
title_sort abacavir methanol 2.5-solvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977439/
https://www.ncbi.nlm.nih.gov/pubmed/21583619
http://dx.doi.org/10.1107/S1600536809027743
work_keys_str_mv AT phamphuongtruct abacavirmethanol25solvate

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