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N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide

In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydro­thia­zolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1)...

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Autores principales: Akkurt, Mehmet, Karaca, Selvi, Cihan, Gökçe, Çapan, Gültaze, Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977697/
https://www.ncbi.nlm.nih.gov/pubmed/21583833
http://dx.doi.org/10.1107/S1600536809012677
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author Akkurt, Mehmet
Karaca, Selvi
Cihan, Gökçe
Çapan, Gültaze
Büyükgüngör, Orhan
author_facet Akkurt, Mehmet
Karaca, Selvi
Cihan, Gökçe
Çapan, Gültaze
Büyükgüngör, Orhan
author_sort Akkurt, Mehmet
collection PubMed
description In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydro­thia­zolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1):0.49 (1) ratio. An intra­molecular N—H⋯S hydrogen bond generates an S(5) ring motif. The two independent mol­ecules are linked into a dimer by two N—H⋯O hydrogen bonds, forming an R (2) (2)(10) ring motif. The crystal structure features inter­molecular C—H⋯π and π–π stacking [centroid–centroid distance = 3.679 (1) Å] inter­actions. C—H⋯O and C—H⋯F inter­actions are also present.
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spelling pubmed-29776972010-12-30 N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide Akkurt, Mehmet Karaca, Selvi Cihan, Gökçe Çapan, Gültaze Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydro­thia­zolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1):0.49 (1) ratio. An intra­molecular N—H⋯S hydrogen bond generates an S(5) ring motif. The two independent mol­ecules are linked into a dimer by two N—H⋯O hydrogen bonds, forming an R (2) (2)(10) ring motif. The crystal structure features inter­molecular C—H⋯π and π–π stacking [centroid–centroid distance = 3.679 (1) Å] inter­actions. C—H⋯O and C—H⋯F inter­actions are also present. International Union of Crystallography 2009-04-08 /pmc/articles/PMC2977697/ /pubmed/21583833 http://dx.doi.org/10.1107/S1600536809012677 Text en © Akkurt et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Akkurt, Mehmet
Karaca, Selvi
Cihan, Gökçe
Çapan, Gültaze
Büyükgüngör, Orhan
N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title_full N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title_fullStr N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title_full_unstemmed N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title_short N′-[(2Z)-3-Allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
title_sort n′-[(2z)-3-allyl-4-oxo-1,3-thia­zolidin-2-yl­idene]-5-fluoro-3-phenyl-1h-indole-2-carbohydrazide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977697/
https://www.ncbi.nlm.nih.gov/pubmed/21583833
http://dx.doi.org/10.1107/S1600536809012677
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