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N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydrothiazolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1)...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977697/ https://www.ncbi.nlm.nih.gov/pubmed/21583833 http://dx.doi.org/10.1107/S1600536809012677 |
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author | Akkurt, Mehmet Karaca, Selvi Cihan, Gökçe Çapan, Gültaze Büyükgüngör, Orhan |
author_facet | Akkurt, Mehmet Karaca, Selvi Cihan, Gökçe Çapan, Gültaze Büyükgüngör, Orhan |
author_sort | Akkurt, Mehmet |
collection | PubMed |
description | In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydrothiazolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1):0.49 (1) ratio. An intramolecular N—H⋯S hydrogen bond generates an S(5) ring motif. The two independent molecules are linked into a dimer by two N—H⋯O hydrogen bonds, forming an R (2) (2)(10) ring motif. The crystal structure features intermolecular C—H⋯π and π–π stacking [centroid–centroid distance = 3.679 (1) Å] interactions. C—H⋯O and C—H⋯F interactions are also present. |
format | Text |
id | pubmed-2977697 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29776972010-12-30 N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide Akkurt, Mehmet Karaca, Selvi Cihan, Gökçe Çapan, Gültaze Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(17)FN(4)O(2)S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydrothiazolyl ring. The –CH2CH=CH(2) substituent is disordered over two positions in a 0.51 (1):0.49 (1) ratio. An intramolecular N—H⋯S hydrogen bond generates an S(5) ring motif. The two independent molecules are linked into a dimer by two N—H⋯O hydrogen bonds, forming an R (2) (2)(10) ring motif. The crystal structure features intermolecular C—H⋯π and π–π stacking [centroid–centroid distance = 3.679 (1) Å] interactions. C—H⋯O and C—H⋯F interactions are also present. International Union of Crystallography 2009-04-08 /pmc/articles/PMC2977697/ /pubmed/21583833 http://dx.doi.org/10.1107/S1600536809012677 Text en © Akkurt et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Akkurt, Mehmet Karaca, Selvi Cihan, Gökçe Çapan, Gültaze Büyükgüngör, Orhan N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title |
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title_full |
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title_fullStr |
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title_full_unstemmed |
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title_short |
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide |
title_sort | n′-[(2z)-3-allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1h-indole-2-carbohydrazide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977697/ https://www.ncbi.nlm.nih.gov/pubmed/21583833 http://dx.doi.org/10.1107/S1600536809012677 |
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