1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide

In the mol­ecule of the title compound, C(18)H(16)F(2)N(4)O(2), the 1,2,4-triazole ring forms dihedral angles of 3.6 (2) and 14.9 (6)° with the 4-difluoro­meth­oxy-substituted benzene ring and the 2,3-dimethyl-substituted benzene ring, respectively. The OCHF(2) group is twisted away from the plane o...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Guang, Huang, Guo-Bo, Zhu, Bing-Chun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977702/
https://www.ncbi.nlm.nih.gov/pubmed/21583838
http://dx.doi.org/10.1107/S160053680901263X
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author Wang, Yu-Guang
Huang, Guo-Bo
Zhu, Bing-Chun
author_facet Wang, Yu-Guang
Huang, Guo-Bo
Zhu, Bing-Chun
author_sort Wang, Yu-Guang
collection PubMed
description In the mol­ecule of the title compound, C(18)H(16)F(2)N(4)O(2), the 1,2,4-triazole ring forms dihedral angles of 3.6 (2) and 14.9 (6)° with the 4-difluoro­meth­oxy-substituted benzene ring and the 2,3-dimethyl-substituted benzene ring, respectively. The OCHF(2) group is twisted away from the plane of the benzene ring, as shown by the C—O—C—C torsion angle of 145.8 (2)°. The conformation is stabilized by an inter­molecular N—H⋯N hydrogen bond. In the crystal, short C—H⋯O inter­actions lead to chains of mol­ecules.
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spelling pubmed-29777022010-12-30 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide Wang, Yu-Guang Huang, Guo-Bo Zhu, Bing-Chun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(18)H(16)F(2)N(4)O(2), the 1,2,4-triazole ring forms dihedral angles of 3.6 (2) and 14.9 (6)° with the 4-difluoro­meth­oxy-substituted benzene ring and the 2,3-dimethyl-substituted benzene ring, respectively. The OCHF(2) group is twisted away from the plane of the benzene ring, as shown by the C—O—C—C torsion angle of 145.8 (2)°. The conformation is stabilized by an inter­molecular N—H⋯N hydrogen bond. In the crystal, short C—H⋯O inter­actions lead to chains of mol­ecules. International Union of Crystallography 2009-04-10 /pmc/articles/PMC2977702/ /pubmed/21583838 http://dx.doi.org/10.1107/S160053680901263X Text en © Wang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Yu-Guang
Huang, Guo-Bo
Zhu, Bing-Chun
1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title_full 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title_fullStr 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title_full_unstemmed 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title_short 1-[4-(Difluoromethoxy)phenyl]-N-(2,3-dimethylphenyl)-1H-1,2,4-triazole-3-carboxamide
title_sort 1-[4-(difluoromethoxy)phenyl]-n-(2,3-dimethylphenyl)-1h-1,2,4-triazole-3-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977702/
https://www.ncbi.nlm.nih.gov/pubmed/21583838
http://dx.doi.org/10.1107/S160053680901263X
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