(+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol

The title compound, C(25)H(27)NO(2), was obtained as the product of a Grignard reagent and an inter­mediate ester synthesized from L-(-)-proline. The asymmetric unit contains two independent mol­ecules, both of which feature an intra­molecular O—H⋯N hydrogen bond. In one of the mol­ecules, the pyrro...

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Detalles Bibliográficos
Autores principales: Jin, Jia, Xue, Si-Jia, Li, Xue-Fei, Fang, Zhi-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977718/
https://www.ncbi.nlm.nih.gov/pubmed/21583854
http://dx.doi.org/10.1107/S1600536809011817
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author Jin, Jia
Xue, Si-Jia
Li, Xue-Fei
Fang, Zhi-Kun
author_facet Jin, Jia
Xue, Si-Jia
Li, Xue-Fei
Fang, Zhi-Kun
author_sort Jin, Jia
collection PubMed
description The title compound, C(25)H(27)NO(2), was obtained as the product of a Grignard reagent and an inter­mediate ester synthesized from L-(-)-proline. The asymmetric unit contains two independent mol­ecules, both of which feature an intra­molecular O—H⋯N hydrogen bond. In one of the mol­ecules, the pyrrolidine ring is disordered over two orientations in a 0.63 (3):0.37 (3) ratio.
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spelling pubmed-29777182010-12-30 (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol Jin, Jia Xue, Si-Jia Li, Xue-Fei Fang, Zhi-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(25)H(27)NO(2), was obtained as the product of a Grignard reagent and an inter­mediate ester synthesized from L-(-)-proline. The asymmetric unit contains two independent mol­ecules, both of which feature an intra­molecular O—H⋯N hydrogen bond. In one of the mol­ecules, the pyrrolidine ring is disordered over two orientations in a 0.63 (3):0.37 (3) ratio. International Union of Crystallography 2009-04-18 /pmc/articles/PMC2977718/ /pubmed/21583854 http://dx.doi.org/10.1107/S1600536809011817 Text en © Jin et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jin, Jia
Xue, Si-Jia
Li, Xue-Fei
Fang, Zhi-Kun
(+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title_full (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title_fullStr (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title_full_unstemmed (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title_short (+)-[1-(4-Methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
title_sort (+)-[1-(4-methoxy­benz­yl)pyrrolidin-2-yl]diphenyl­methanol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977718/
https://www.ncbi.nlm.nih.gov/pubmed/21583854
http://dx.doi.org/10.1107/S1600536809011817
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AT lixuefei 14methoxybenzylpyrrolidin2yldiphenylmethanol
AT fangzhikun 14methoxybenzylpyrrolidin2yldiphenylmethanol

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