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(1R,3S,5R,6S)-6-Acetoxy-8-methyl-3-(p-tolylsulfonyloxy)-8-azoniabicyclo[3.2.1]octane (2R,3R)-2,3-bis(benzoyloxy)-3-carboxypropanoate
The title compound, C(17)H(24)NO(5)S(+)·C(18)H(13)O(8) (−), is the key intermediate during the preparation of lesatropane [systematic name (1R,3S,5R,6S)-6-acetoxy-3-(4-methylphenylsulfonyloxy)tropane], a potential antiglaucoma agent. The tertiary N atom of the tropane ring is involved in intermol...
Autores principales: | Yang, Li-Min, Xie, Yi-Fan, Gu, Ya-Fang, Chen, Hong-Zhuan, Lu, Yang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977720/ https://www.ncbi.nlm.nih.gov/pubmed/21583856 http://dx.doi.org/10.1107/S1600536809012732 |
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