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6′-Methyl-1′,2′,3′,4′-tetrahydrospirocyclohexane-2′-quinazolin-4′-one
The title compound, C(14)H(18)N(2)O, was synthesized by the reaction of cyclohexanone and 2-amino-5-methylbenzonitrile. In the molecule, the cyclohexane ring displays a chair conformation, whereas the 1,3-diazacyclohexane moiety of the bicyclic system has a sofa conformation with the spiro C...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977775/ https://www.ncbi.nlm.nih.gov/pubmed/21583911 http://dx.doi.org/10.1107/S1600536809014111 |
Sumario: | The title compound, C(14)H(18)N(2)O, was synthesized by the reaction of cyclohexanone and 2-amino-5-methylbenzonitrile. In the molecule, the cyclohexane ring displays a chair conformation, whereas the 1,3-diazacyclohexane moiety of the bicyclic system has a sofa conformation with the spiro C atom displaced by 0.603 (2) Å from the rest of the atoms of the 1,3-diazacyclohexane ring [planar within 0.052 (2) Å]. Molecules are linked into centrosymmetric dimers via N—H⋯O hydrogen bonds. |
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