3β,12β,14α-Trihydroxy­pregnan-20-one

The title compound, C(21)H(34)O(4), is a steriod of the pregnane family prepared by the sequential oxidation and reduction of 3β,12β-diacet­oxy-20-ethyl­enedioxy­pregnan-14-ene. The con­formations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope con...

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Detalles Bibliográficos
Autores principales: Shi, Hefang, Li, Yingxia
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977780/
https://www.ncbi.nlm.nih.gov/pubmed/21583916
http://dx.doi.org/10.1107/S1600536809013853
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author Shi, Hefang
Li, Yingxia
author_facet Shi, Hefang
Li, Yingxia
author_sort Shi, Hefang
collection PubMed
description The title compound, C(21)H(34)O(4), is a steriod of the pregnane family prepared by the sequential oxidation and reduction of 3β,12β-diacet­oxy-20-ethyl­enedioxy­pregnan-14-ene. The con­formations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope conformation. All the rings are trans-fused and an intra­molecular O—H⋯O hydrogen bond occurs. In the crystal structure, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into a two-dimensional network.
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spelling pubmed-29777802010-12-30 3β,12β,14α-Trihydroxy­pregnan-20-one Shi, Hefang Li, Yingxia Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(34)O(4), is a steriod of the pregnane family prepared by the sequential oxidation and reduction of 3β,12β-diacet­oxy-20-ethyl­enedioxy­pregnan-14-ene. The con­formations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope conformation. All the rings are trans-fused and an intra­molecular O—H⋯O hydrogen bond occurs. In the crystal structure, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into a two-dimensional network. International Union of Crystallography 2009-04-25 /pmc/articles/PMC2977780/ /pubmed/21583916 http://dx.doi.org/10.1107/S1600536809013853 Text en © Shi and Li 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Shi, Hefang
Li, Yingxia
3β,12β,14α-Trihydroxy­pregnan-20-one
title 3β,12β,14α-Trihydroxy­pregnan-20-one
title_full 3β,12β,14α-Trihydroxy­pregnan-20-one
title_fullStr 3β,12β,14α-Trihydroxy­pregnan-20-one
title_full_unstemmed 3β,12β,14α-Trihydroxy­pregnan-20-one
title_short 3β,12β,14α-Trihydroxy­pregnan-20-one
title_sort 3β,12β,14α-trihydroxy­pregnan-20-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977780/
https://www.ncbi.nlm.nih.gov/pubmed/21583916
http://dx.doi.org/10.1107/S1600536809013853
work_keys_str_mv AT shihefang 3b12b14atrihydroxypregnan20one
AT liyingxia 3b12b14atrihydroxypregnan20one

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