3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine

In the mol­ecule of the title compound, C(26)H(22)N(4)S(2), the pyrazole ring is oriented at a dihedral angle of 0.85 (3)° with respect to the adjacent naphthyridine ring, while the other ring of naphthyridine adopts an envelope conformation. The dihedral angle between phenyl and pyrazole rings is 8...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Juhua, Han, Zhengguo, Ma, Ning, Tu, Shujiang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977787/
https://www.ncbi.nlm.nih.gov/pubmed/21583923
http://dx.doi.org/10.1107/S1600536809014810
_version_ 1782191188346929152
author Peng, Juhua
Han, Zhengguo
Ma, Ning
Tu, Shujiang
author_facet Peng, Juhua
Han, Zhengguo
Ma, Ning
Tu, Shujiang
author_sort Peng, Juhua
collection PubMed
description In the mol­ecule of the title compound, C(26)H(22)N(4)S(2), the pyrazole ring is oriented at a dihedral angle of 0.85 (3)° with respect to the adjacent naphthyridine ring, while the other ring of naphthyridine adopts an envelope conformation. The dihedral angle between phenyl and pyrazole rings is 87.65 (3)°. In the crystal structure, weak inter­molecular C—H⋯N inter­actions link the mol­ecules into chains. The π–π contacts between the naphthyridine rings and the naphthyridine and thio­phene rings [centroid–centroid distances = 3.766 (3) and 3.878 (3) Å] may further stabilize the structure. A weak C—H⋯π inter­action is also present.
format Text
id pubmed-2977787
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29777872010-12-30 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine Peng, Juhua Han, Zhengguo Ma, Ning Tu, Shujiang Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(26)H(22)N(4)S(2), the pyrazole ring is oriented at a dihedral angle of 0.85 (3)° with respect to the adjacent naphthyridine ring, while the other ring of naphthyridine adopts an envelope conformation. The dihedral angle between phenyl and pyrazole rings is 87.65 (3)°. In the crystal structure, weak inter­molecular C—H⋯N inter­actions link the mol­ecules into chains. The π–π contacts between the naphthyridine rings and the naphthyridine and thio­phene rings [centroid–centroid distances = 3.766 (3) and 3.878 (3) Å] may further stabilize the structure. A weak C—H⋯π inter­action is also present. International Union of Crystallography 2009-04-25 /pmc/articles/PMC2977787/ /pubmed/21583923 http://dx.doi.org/10.1107/S1600536809014810 Text en © Peng et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Peng, Juhua
Han, Zhengguo
Ma, Ning
Tu, Shujiang
3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title_full 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title_fullStr 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title_full_unstemmed 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title_short 3,6-Dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1H-pyrazolo[3,4-b][1,6]naphthyridine
title_sort 3,6-dimethyl-1-phenyl-4-(2-thien­yl)-8-(2-thienylmethyl­ene)-5,6,7,8-tetra­hydro-1h-pyrazolo[3,4-b][1,6]naphthyridine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977787/
https://www.ncbi.nlm.nih.gov/pubmed/21583923
http://dx.doi.org/10.1107/S1600536809014810
work_keys_str_mv AT pengjuhua 36dimethyl1phenyl42thienyl82thienylmethylene5678tetrahydro1hpyrazolo34b16naphthyridine
AT hanzhengguo 36dimethyl1phenyl42thienyl82thienylmethylene5678tetrahydro1hpyrazolo34b16naphthyridine
AT maning 36dimethyl1phenyl42thienyl82thienylmethylene5678tetrahydro1hpyrazolo34b16naphthyridine
AT tushujiang 36dimethyl1phenyl42thienyl82thienylmethylene5678tetrahydro1hpyrazolo34b16naphthyridine

Ejemplares similares