New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature

Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainly...

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Detalles Bibliográficos
Autores principales: Santos Andrade, Elvis Henrique, Pan, Pedro Mario, da Silva, Paula F. Ramalho, Gadelha, Ary
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977938/
https://www.ncbi.nlm.nih.gov/pubmed/21076684
http://dx.doi.org/10.1155/2010/573252
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author Santos Andrade, Elvis Henrique
Pan, Pedro Mario
da Silva, Paula F. Ramalho
Gadelha, Ary
author_facet Santos Andrade, Elvis Henrique
Pan, Pedro Mario
da Silva, Paula F. Ramalho
Gadelha, Ary
author_sort Santos Andrade, Elvis Henrique
collection PubMed
description Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems. We report a case of a 39-year-old schizophrenic male patient that was diagnosed with a macroprolactinoma 8 years after his first psychotic episode. The association of Schizophrenia and prolactinoma represents a clinical challenge once the treatment of one disease can exacerbate the symptoms of the other.
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spelling pubmed-29779382010-11-12 New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature Santos Andrade, Elvis Henrique Pan, Pedro Mario da Silva, Paula F. Ramalho Gadelha, Ary Case Rep Med Case Report Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders. Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems. We report a case of a 39-year-old schizophrenic male patient that was diagnosed with a macroprolactinoma 8 years after his first psychotic episode. The association of Schizophrenia and prolactinoma represents a clinical challenge once the treatment of one disease can exacerbate the symptoms of the other. Hindawi Publishing Corporation 2010 2010-11-10 /pmc/articles/PMC2977938/ /pubmed/21076684 http://dx.doi.org/10.1155/2010/573252 Text en Copyright © 2010 Elvis Henrique Santos Andrade et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Santos Andrade, Elvis Henrique
Pan, Pedro Mario
da Silva, Paula F. Ramalho
Gadelha, Ary
New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_full New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_fullStr New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_full_unstemmed New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_short New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature
title_sort new insights in the management of antipsychotics in the treatment of schizophrenia in a patient with prolactinoma: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977938/
https://www.ncbi.nlm.nih.gov/pubmed/21076684
http://dx.doi.org/10.1155/2010/573252
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