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Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
BACKGROUND: Dyskinesias associated with involuntary movements and painful muscle contractions are a common and severe complication of standard levodopa (L-DOPA, L-3,4-dihydroxyphenylalanine) therapy for Parkinson's disease. Pathologic neuroplasticity leading to hyper-responsive dopamine recepto...
Autores principales: | Cantuti-Castelvetri, Ippolita, Hernandez, Ledia F., Keller-McGandy, Christine E., Kett, Lauren R., Landy, Alex, Hollingsworth, Zane R., Saka, Esen, Crittenden, Jill R., Nillni, Eduardo A., Young, Anne B., Standaert, David G., Graybiel, Ann M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978093/ https://www.ncbi.nlm.nih.gov/pubmed/21085660 http://dx.doi.org/10.1371/journal.pone.0013861 |
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