Cyclophilin B Interacts with Sodium-Potassium ATPase and Is Required for Pump Activity in Proximal Tubule Cells of the Kidney

Cyclophilins (Cyps), the intracellular receptors for Cyclosporine A (CsA), are responsible for peptidyl-prolyl cis-trans isomerisation and for chaperoning several membrane proteins. Those functions are inhibited upon CsA binding. Albeit its great benefits as immunosuppressant, the use of CsA has bee...

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Detalles Bibliográficos
Autores principales: Suñé, Guillermo, Sarró, Eduard, Puigmulé, Marta, López-Hellín, Joan, Zufferey, Madeleine, Pertel, Thomas, Luban, Jeremy, Meseguer, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978098/
https://www.ncbi.nlm.nih.gov/pubmed/21085665
http://dx.doi.org/10.1371/journal.pone.0013930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978098/
https://www.ncbi.nlm.nih.gov/pubmed/21085665
http://dx.doi.org/10.1371/journal.pone.0013930

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