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Cyclophilin B Interacts with Sodium-Potassium ATPase and Is Required for Pump Activity in Proximal Tubule Cells of the Kidney
Cyclophilins (Cyps), the intracellular receptors for Cyclosporine A (CsA), are responsible for peptidyl-prolyl cis-trans isomerisation and for chaperoning several membrane proteins. Those functions are inhibited upon CsA binding. Albeit its great benefits as immunosuppressant, the use of CsA has bee...
Autores principales: | Suñé, Guillermo, Sarró, Eduard, Puigmulé, Marta, López-Hellín, Joan, Zufferey, Madeleine, Pertel, Thomas, Luban, Jeremy, Meseguer, Anna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978098/ https://www.ncbi.nlm.nih.gov/pubmed/21085665 http://dx.doi.org/10.1371/journal.pone.0013930 |
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