Cargando…

Angiogenin Levels and ANG Genotypes: Dysregulation in Amyotrophic Lateral Sclerosis

OBJECTIVE: To determine whether 5 single nucleotide polymorphisms (SNPs) associate with ALS in 3 different populations. We also assessed the contribution of genotype to angiogenin levels in plasma and CSF. METHODS: Allelic association statistics were calculated for polymorphisms in the ANG gene in 8...

Descripción completa

Detalles Bibliográficos
Autores principales:	McLaughlin, Russell Lewis, Phukan, Julie, McCormack, William, Lynch, David S., Greenway, Matthew, Cronin, Simon, Saunders, Jean, Slowik, Agnieska, Tomik, Barbara, Andersen, Peter M., Bradley, Daniel G., Jakeman, Phil, Hardiman, Orla
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978104/ https://www.ncbi.nlm.nih.gov/pubmed/21085671 http://dx.doi.org/10.1371/journal.pone.0015402

Ejemplares similares

Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis
por: Fernández-Santiago, Rubén, et al.
Publicado: (2009)

Lack of unique neuropathology in amyotrophic lateral sclerosis associated with p.K54E angiogenin (ANG) mutation
por: Kirby, J, et al.
Publicado: (2013)

Angiogenin (ANG)—Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2021)

Cognitive and neuropsychiatric endophenotypes in amyotrophic lateral sclerosis
por: Costello, Emmet, et al.
Publicado: (2023)

Computational and Functional Characterization of Angiogenin Mutations, and Correlation with Amyotrophic Lateral Sclerosis
por: Padhi, Aditya K., et al.
Publicado: (2014)

Mechanisms of Loss of Functions of Human Angiogenin Variants Implicated in Amyotrophic Lateral Sclerosis
por: Padhi, Aditya K., et al.
Publicado: (2012)

Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase
por: Aparicio-Erriu, Isabela M., et al.
Publicado: (2012)

The C9orf72 expansion is associated with accelerated respiratory function decline in a large Amyotrophic Lateral Sclerosis cohort
por: Rooney, James, et al.
Publicado: (2019)

Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis
por: Bradshaw, William J., et al.
Publicado: (2017)

A Cross‐sectional population‐based investigation into behavioral change in amyotrophic lateral sclerosis: subphenotypes, staging, cognitive predictors, and survival
por: Burke, Tom, et al.
Publicado: (2017)

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study
por: Byrne, Susan, et al.
Publicado: (2012)

Angiogenin mutations in Hungarian patients with amyotrophic lateral sclerosis: Clinical, genetic, computational, and functional analyses
por: Tripolszki, Kornélia, et al.
Publicado: (2019)

Brainstem–cortex disconnection in amyotrophic lateral sclerosis: bulbar impairment, genotype associations, asymptomatic changes and biomarker opportunities
por: Tahedl, Marlene, et al.
Publicado: (2023)

Brainstem pathology in amyotrophic lateral sclerosis and primary lateral sclerosis: A longitudinal neuroimaging study
por: Bede, Peter, et al.
Publicado: (2019)

The involvement of language‐associated networks, tracts, and cortical regions in frontotemporal dementia and amyotrophic lateral sclerosis: Structural and functional alterations
por: Tahedl, Marlene, et al.
Publicado: (2023)

Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients
por: Robinson-Cohen, Cassianne, et al.
Publicado: (2016)

Mismatch Negativity as an Indicator of Cognitive Sub-Domain Dysfunction in Amyotrophic Lateral Sclerosis
por: Iyer, Parameswaran Mahadeva, et al.
Publicado: (2017)

Survival prediction in Amyotrophic lateral sclerosis based on MRI measures and clinical characteristics
por: Schuster, Christina, et al.
Publicado: (2017)

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
por: McLaughlin, Russell L., et al.
Publicado: (2017)

Thalamic, hippocampal and basal ganglia pathology in primary lateral sclerosis and amyotrophic lateral sclerosis: Evidence from quantitative imaging data
por: Finegan, Eoin, et al.
Publicado: (2020)

Human angiogenin, an organogenic protein.
por: Riordan, J. F., et al.
Publicado: (1988)

Progressive brainstem pathology in motor neuron diseases: Imaging data from amyotrophic lateral sclerosis and primary lateral sclerosis
por: Bede, Peter, et al.
Publicado: (2020)

The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis
por: Tomik, Jerzy, et al.
Publicado: (2017)

Crystal structures of murine angiogenin-2 and -3 – probing ‘structure – function’ relationships amongst angiogenin homologues
por: Iyer, Shalini, et al.
Publicado: (2013)

Predicting prognosis in amyotrophic lateral sclerosis: a simple algorithm
por: Elamin, Marwa, et al.
Publicado: (2015)

Angiogenin in age-related macular degeneration
por: Skeie, Jessica M., et al.
Publicado: (2011)

Mutational dynamics of murine angiogenin duplicates
por: Codoñer, Francisco M, et al.
Publicado: (2010)

Angiogenin and osteopontin and coronary collateral circulation
por: Beuy, Joob, et al.
Publicado: (2019)

Angiogenin and Copper Crossing in Wound Healing
por: Cucci, Lorena Maria, et al.
Publicado: (2021)

Muscle strength can better differentiate between gradations of functional performance than muscle quality in healthy 50–70 y women
por: Francis, Peter, et al.
Publicado: (2017)

“Switchboard” malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis
por: Chipika, Rangariroyashe H., et al.
Publicado: (2020)

MRI data confirm the selective involvement of thalamic and amygdalar nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis
por: Chipika, Rangariroyashe H., et al.
Publicado: (2020)

Prediction of caregiver quality of life in amyotrophic lateral sclerosis using explainable machine learning
por: Antoniadi, Anna Markella, et al.
Publicado: (2021)

Estimated Familial Amyotrophic Lateral Sclerosis Proportion: A Literature Review and Meta-analysis
por: Barberio, Julie, et al.
Publicado: (2023)

Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study
por: Schuster, Christina, et al.
Publicado: (2016)

Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis
por: Dukic, Stefan, et al.
Publicado: (2021)

Angiogenin in Parkinson Disease Models: Role of Akt Phosphorylation and Evaluation of AAV-Mediated Angiogenin Expression in MPTP Treated Mice
por: Steidinger, Trent U., et al.
Publicado: (2013)

"Getting the lead out" in Hartford, Connecticut: a multifaceted lead-poisoning awareness campaign.
por: McLaughlin, Tara J, et al.
Publicado: (2004)

Virtual brain biopsies in amyotrophic lateral sclerosis: Diagnostic classification based on in vivo pathological patterns
por: Bede, Peter, et al.
Publicado: (2017)

ANGDelMut – a web-based tool for predicting and analyzing functional loss mechanisms of amyotrophic lateral sclerosis-associated angiogenin mutations
por: Padhi, Aditya K, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ad84m98b6m1o1gnver7cq7mtv3