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The VHL-dependent regulation of microRNAs in renal cancer

BACKGROUND: The commonest histological type of renal cancer, clear cell renal cell carcinoma (cc RCC), is associated with genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumour suppressor. VHL inactivation leads to induction of hypoxia-inducible factors (HIFs) and a hypoxic pattern of...

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Detalles Bibliográficos
Autores principales:	Neal, Calida S, Michael, Michael Z, Rawlings, Lesley H, Van der Hoek, Mark B, Gleadle, Jonathan M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978113/ https://www.ncbi.nlm.nih.gov/pubmed/20964835 http://dx.doi.org/10.1186/1741-7015-8-64

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