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Raloxifene inhibits tumor growth and lymph node metastasis in a xenograft model of metastatic mammary cancer

BACKGROUND: The effects of raloxifene, a novel selective estrogen receptor modulator, were studied in a mouse metastatic mammary cancer model expressing cytoplasmic ERα. METHODS: Mammary tumors, induced by inoculation of syngeneic BALB/c mice with BJMC3879luc2 cells, were subsequently treated with r...

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Detalles Bibliográficos
Autores principales: Shibata, Masa-Aki, Morimoto, Junji, Shibata, Eiko, Kurose, Hitomi, Akamatsu, Kanako, Li, Zhong-Lian, Kusakabe, Moriaki, Ohmichi, Masahide, Otsuki, Yoshinori
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978204/
https://www.ncbi.nlm.nih.gov/pubmed/20958960
http://dx.doi.org/10.1186/1471-2407-10-566