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Epigenetic inactivation of the NORE1 gene correlates with malignant progression of colorectal tumors

BACKGROUND: NORE1 (RASSF5) is a newly described member of the RASSF family with Ras effector function. NORE1 expression is frequently inactivated by aberrant promoter hypermethylation in many human cancers, suggesting that NORE1 might be a putative tumor suppressor. However, expression and mutation...

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Detalles Bibliográficos
Autores principales:	Lee, Chang Kyun, Lee, Jin-Hee, Lee, Min-Goo, Jeong, Seong-In, Ha, Tae-Kyu, Kang, Min-Ju, Ryu, Byung-Kyu, Hwangbo, Young, Shim, Jae-Jun, Jang, Jae Young, Lee, Kil Yeon, Kim, Hyo Jong, Chi, Sung-Gil
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978205/ https://www.ncbi.nlm.nih.gov/pubmed/20969767 http://dx.doi.org/10.1186/1471-2407-10-577

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