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Increased spinal prodynorphin gene expression in reinflammation-associated hyperalgesia after neonatal inflammatory insult

BACKGROUND: Neuroplasticity induced by neonatal inflammation is the consequence of a combination of activity-dependent changes in neurons. We investigated neuronal sensitivity to a noxious stimulus in a rat model of neonatal hind-paw peripheral inflammation and assessed changes in pain behaviour at...

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Detalles Bibliográficos
Autores principales: Lin, Jack Yu-Shih, Cheng, Yu-Che, Chen, Julia Yi-Ru, Chien, Chih-Cheng, Lin, Shih-Chang, Wen, Yeong-Ray, Tsou, Tsung-Shan, Ling, Qing-Dong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978219/
https://www.ncbi.nlm.nih.gov/pubmed/20973986
http://dx.doi.org/10.1186/1471-2202-11-139