Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

Herein, we study the nanomechanical characteristics of single DNA molecules in the presence of DNA binders, including intercalating agents (ethidium bromide and doxorubicin), a minor groove binder (netropsin) and a typical alkylating damaging agent (cisplatin). We have used magnetic tweezers manipul...

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Detalles Bibliográficos
Autores principales: Salerno, Domenico, Brogioli, Doriano, Cassina, Valeria, Turchi, Diana, Beretta, Giovanni Luca, Seruggia, Davide, Ziano, Roberto, Zunino, Franco, Mantegazza, Francesco
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978368/
https://www.ncbi.nlm.nih.gov/pubmed/20601682
http://dx.doi.org/10.1093/nar/gkq597

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