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Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNA(Gln) formation
The molecular basis of the genetic code relies on the specific ligation of amino acids to their cognate tRNA molecules. However, two pathways exist for the formation of Gln-tRNA(Gln). The evolutionarily older indirect route utilizes a non-discriminating glutamyl-tRNA synthetase (ND-GluRS) that can f...
Autores principales: | Nureki, Osamu, O’Donoghue, Patrick, Watanabe, Nobuhisa, Ohmori, Atsuhiko, Oshikane, Hiroyuki, Araiso, Yuhei, Sheppard, Kelly, Söll, Dieter, Ishitani, Ryuichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978374/ https://www.ncbi.nlm.nih.gov/pubmed/20601684 http://dx.doi.org/10.1093/nar/gkq605 |
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