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Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting

PURPOSE: To evaluate the outcome of shock wave lithotripsy (SWL) as monotherapy for solitary renal stones larger than 2 cm without ureteral stenting. MATERIALS AND METHODS: Our retrospective study included patients with solitary renal radio opaque stones larger than 2 cm treated with SWL using elect...

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Autores principales: Rajaian, Shanmugasundaram, Kumar, Santosh, Gopalakrishnan, Ganesh, Chacko, Ninan K., Devasia, Antony, Kekre, Nitin S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978434/
https://www.ncbi.nlm.nih.gov/pubmed/21116354
http://dx.doi.org/10.4103/0970-1591.70568
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author Rajaian, Shanmugasundaram
Kumar, Santosh
Gopalakrishnan, Ganesh
Chacko, Ninan K.
Devasia, Antony
Kekre, Nitin S.
author_facet Rajaian, Shanmugasundaram
Kumar, Santosh
Gopalakrishnan, Ganesh
Chacko, Ninan K.
Devasia, Antony
Kekre, Nitin S.
author_sort Rajaian, Shanmugasundaram
collection PubMed
description PURPOSE: To evaluate the outcome of shock wave lithotripsy (SWL) as monotherapy for solitary renal stones larger than 2 cm without ureteral stenting. MATERIALS AND METHODS: Our retrospective study included patients with solitary renal radio opaque stones larger than 2 cm treated with SWL using electromagnetic Dornier Compact S lithotripter device (Wessling, Germany) for a period of 3 years (September 2002-2005). Stone clearance was assessed at 1 week, 1 month, and 3 months with plain X-rays of kidney, ureter, and bladder region, ultrasonography, and tomograms. Stone-free status, morbidity of the procedure, and fate of clinically insignificant residual fragments (CIRF) were studied. A stone-free state was defined as no radiologic evidence of stone. Success was defined as complete clearance + CIRF. RESULTS: Fifty-five patients, aged 11–65 years (mean 49.8) underwent SWL. Of them, only two were children. Male-to-female ratio was 3:1. The stone size was 21–28 mm (average 24 mm). The mean number of shocks were 3732 (range 724–12,100) and average energy level was 14 kV (range 11–16 kV). The mean follow-up was 18 months (range 3–22 months). Over all, stone-free status was achieved in 50% and success in 81% at 3 months. Stone clearance was not affected by stone location. Stones <25 mm had better stone-free rate (54.16% vs. 28.5%) and lesser CIRF (14.6% vs. 28.5%) when compared to larger stones (>26 mm) (P = –0.10). Of 54 patients, 39 developed steinstrasse with mean length of 3.2 cm (range 1.4–6.2 cm) and only four required intervention. Effectiveness quotient (EQ) for SWL monotherapy for solitary renal stones more than 2 cm was 25.3%. The EQ for stones <25 mm and those more than 25 mm were 28.4% and 10% (P = –0.12), respectively. There was a lesser trend of difference between stones with size <25 and more than 25 mm. During the last review, the overall stone-free rate was 67.2%. CONCLUSIONS: SWL monotherapy was safe but significantly less effective for solitary renal stones larger than 2 cm. It can only be suggested to those who refuse surgical intervention. Pretreatment DJ stenting is not mandatory when closer follow-up is ensured.
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spelling pubmed-29784342010-11-29 Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting Rajaian, Shanmugasundaram Kumar, Santosh Gopalakrishnan, Ganesh Chacko, Ninan K. Devasia, Antony Kekre, Nitin S. Indian J Urol Original Article PURPOSE: To evaluate the outcome of shock wave lithotripsy (SWL) as monotherapy for solitary renal stones larger than 2 cm without ureteral stenting. MATERIALS AND METHODS: Our retrospective study included patients with solitary renal radio opaque stones larger than 2 cm treated with SWL using electromagnetic Dornier Compact S lithotripter device (Wessling, Germany) for a period of 3 years (September 2002-2005). Stone clearance was assessed at 1 week, 1 month, and 3 months with plain X-rays of kidney, ureter, and bladder region, ultrasonography, and tomograms. Stone-free status, morbidity of the procedure, and fate of clinically insignificant residual fragments (CIRF) were studied. A stone-free state was defined as no radiologic evidence of stone. Success was defined as complete clearance + CIRF. RESULTS: Fifty-five patients, aged 11–65 years (mean 49.8) underwent SWL. Of them, only two were children. Male-to-female ratio was 3:1. The stone size was 21–28 mm (average 24 mm). The mean number of shocks were 3732 (range 724–12,100) and average energy level was 14 kV (range 11–16 kV). The mean follow-up was 18 months (range 3–22 months). Over all, stone-free status was achieved in 50% and success in 81% at 3 months. Stone clearance was not affected by stone location. Stones <25 mm had better stone-free rate (54.16% vs. 28.5%) and lesser CIRF (14.6% vs. 28.5%) when compared to larger stones (>26 mm) (P = –0.10). Of 54 patients, 39 developed steinstrasse with mean length of 3.2 cm (range 1.4–6.2 cm) and only four required intervention. Effectiveness quotient (EQ) for SWL monotherapy for solitary renal stones more than 2 cm was 25.3%. The EQ for stones <25 mm and those more than 25 mm were 28.4% and 10% (P = –0.12), respectively. There was a lesser trend of difference between stones with size <25 and more than 25 mm. During the last review, the overall stone-free rate was 67.2%. CONCLUSIONS: SWL monotherapy was safe but significantly less effective for solitary renal stones larger than 2 cm. It can only be suggested to those who refuse surgical intervention. Pretreatment DJ stenting is not mandatory when closer follow-up is ensured. Medknow Publications 2010 /pmc/articles/PMC2978434/ /pubmed/21116354 http://dx.doi.org/10.4103/0970-1591.70568 Text en © Indian Journal of Urology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Rajaian, Shanmugasundaram
Kumar, Santosh
Gopalakrishnan, Ganesh
Chacko, Ninan K.
Devasia, Antony
Kekre, Nitin S.
Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title_full Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title_fullStr Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title_full_unstemmed Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title_short Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
title_sort outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978434/
https://www.ncbi.nlm.nih.gov/pubmed/21116354
http://dx.doi.org/10.4103/0970-1591.70568
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