INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT

The effect of high fat food in the steady state bioavailability of lithium carbonate (900 or 1200mg daily, in divided doses) was studied in three patients of manic-depressive psychosis in a self-control cross-over design. Serial blood samples were collected by venepuncture until 8 hours following dr...

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Detalles Bibliográficos
Autores principales: Tripathi, S.K., Basu, D., Kulhara, P., Garg, S.K., Sharma, P.L.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1993
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978491/
https://www.ncbi.nlm.nih.gov/pubmed/21743634
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author Tripathi, S.K.
Basu, D.
Kulhara, P.
Garg, S.K.
Sharma, P.L.
author_facet Tripathi, S.K.
Basu, D.
Kulhara, P.
Garg, S.K.
Sharma, P.L.
author_sort Tripathi, S.K.
collection PubMed
description The effect of high fat food in the steady state bioavailability of lithium carbonate (900 or 1200mg daily, in divided doses) was studied in three patients of manic-depressive psychosis in a self-control cross-over design. Serial blood samples were collected by venepuncture until 8 hours following drug administration and lithium was assayed by flame photometry. The results indicated a reduction in the extent of bioavailability of lithium by the high fat food as compared to standard normal diet, in all the three patients studied Caution should be exercised in regard to lithium administration along with food rich in fat content.
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spelling pubmed-29784912011-07-08 INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT Tripathi, S.K. Basu, D. Kulhara, P. Garg, S.K. Sharma, P.L. Indian J Psychiatry Original Article The effect of high fat food in the steady state bioavailability of lithium carbonate (900 or 1200mg daily, in divided doses) was studied in three patients of manic-depressive psychosis in a self-control cross-over design. Serial blood samples were collected by venepuncture until 8 hours following drug administration and lithium was assayed by flame photometry. The results indicated a reduction in the extent of bioavailability of lithium by the high fat food as compared to standard normal diet, in all the three patients studied Caution should be exercised in regard to lithium administration along with food rich in fat content. Medknow Publications 1993 /pmc/articles/PMC2978491/ /pubmed/21743634 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Tripathi, S.K.
Basu, D.
Kulhara, P.
Garg, S.K.
Sharma, P.L.
INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title_full INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title_fullStr INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title_full_unstemmed INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title_short INFLUENCE OF HIGH FAT DIET ON STEADY STATE BIOAVAILABILITY OF LITHIUM CARBONATE IN MANIC DEPRESSIVE PATIENTS - A PRELIMINARY REPORT
title_sort influence of high fat diet on steady state bioavailability of lithium carbonate in manic depressive patients - a preliminary report
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978491/
https://www.ncbi.nlm.nih.gov/pubmed/21743634
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