Therapeutic Immunization with HIV-1 Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART

Although HAART suppresses HIV replication, it is often unable to restore immune homeostasis. Consequently, non-AIDS-defining diseases are increasingly seen in treated individuals. This is attributed to persistent virus expression in reservoirs and to cell activation. Of note, in CD4(+) T cells and m...

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Detalles Bibliográficos
Autores principales: Ensoli, Barbara, Bellino, Stefania, Tripiciano, Antonella, Longo, Olimpia, Francavilla, Vittorio, Marcotullio, Simone, Cafaro, Aurelio, Picconi, Orietta, Paniccia, Giovanni, Scoglio, Arianna, Arancio, Angela, Ariola, Cristina, Ruiz Alvarez, Maria J., Campagna, Massimo, Scaramuzzi, Donato, Iori, Cristina, Esposito, Roberto, Mussini, Cristina, Ghinelli, Florio, Sighinolfi, Laura, Palamara, Guido, Latini, Alessandra, Angarano, Gioacchino, Ladisa, Nicoletta, Soscia, Fabrizio, Mercurio, Vito S., Lazzarin, Adriano, Tambussi, Giuseppe, Visintini, Raffaele, Mazzotta, Francesco, Di Pietro, Massimo, Galli, Massimo, Rusconi, Stefano, Carosi, Giampiero, Torti, Carlo, Di Perri, Giovanni, Bonora, Stefano, Ensoli, Fabrizio, Garaci, Enrico
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978690/
https://www.ncbi.nlm.nih.gov/pubmed/21085635
http://dx.doi.org/10.1371/journal.pone.0013540

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