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Preclinical Deposition of Pathological Prion Protein in Muscle of Experimentally Infected Primates
Prion diseases are transmissible fatal neurodegenerative disorders affecting humans and animals. A central step in disease progression is the accumulation of a misfolded form (PrP(Sc)) of the host encoded prion protein (PrP(C)) in neuronal and non-neuronal tissues. The involvement of peripheral tiss...
Autores principales: | Krasemann, Susanne, Neumann, Melanie, Geissen, Markus, Bodemer, Walter, Kaup, Franz-Josef, Schulz-Schaeffer, Walter, Morel, Nathalie, Aguzzi, Adriano, Glatzel, Markus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978702/ https://www.ncbi.nlm.nih.gov/pubmed/21085647 http://dx.doi.org/10.1371/journal.pone.0013906 |
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