Cargando…
A Role for the Retinoblastoma Protein As a Regulator of Mouse Osteoblast Cell Adhesion: Implications for Osteogenesis and Osteosarcoma Formation
The retinoblastoma protein (pRb) is a cell cycle regulator inactivated in most human cancers. Loss of pRb function results from mutations in the gene coding for pRb or for any of its upstream regulators. Although pRb is predominantly known as a cell cycle repressor, our data point to additional pRb...
Autores principales: | Sosa-García, Bernadette, Gunduz, Volkan, Vázquez-Rivera, Viviana, Cress, W. Douglas, Wright, Gabriela, Bian, Haikuo, Hinds, Philip W., Santiago-Cardona, Pedro G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978706/ https://www.ncbi.nlm.nih.gov/pubmed/21085651 http://dx.doi.org/10.1371/journal.pone.0013954 |
Ejemplares similares
-
The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts
por: Sosa-García, Bernadette, et al.
Publicado: (2015) -
Osteosarcoma: prognosis plateau warrants retinoblastoma pathway targeted therapy
por: Ballatori, Sarah E, et al.
Publicado: (2016) -
Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors
por: Engel, B E, et al.
Publicado: (2013) -
Chemotherapy in Retinoblastoma: Current Approaches
por: Yanık, Özge, et al.
Publicado: (2015) -
Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts
por: Cray, James J., et al.
Publicado: (2013)