PTEN transcript variants caused by illegitimate splicing in “aged” blood samples and EBV-transformed cell lines

PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. Mutations occur in either heritable or sporadic fashion. Sequencing of cDNA from patients and normal individuals often reveals splicing variants (SVs) of PTEN, some of which are non-mutation related. To investigate w...

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Detalles Bibliográficos
Autores principales: Liu, Yunying, Malaviarachchi, Priyangi, Beggs, Marjorie, Emanuel, Peter D.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978886/
https://www.ncbi.nlm.nih.gov/pubmed/20839010
http://dx.doi.org/10.1007/s00439-010-0886-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978886/
https://www.ncbi.nlm.nih.gov/pubmed/20839010
http://dx.doi.org/10.1007/s00439-010-0886-4

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