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PTEN transcript variants caused by illegitimate splicing in “aged” blood samples and EBV-transformed cell lines
PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. Mutations occur in either heritable or sporadic fashion. Sequencing of cDNA from patients and normal individuals often reveals splicing variants (SVs) of PTEN, some of which are non-mutation related. To investigate w...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978886/ https://www.ncbi.nlm.nih.gov/pubmed/20839010 http://dx.doi.org/10.1007/s00439-010-0886-4 |