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Expression Level, Evolutionary Rate, and the Cost of Expression
There is great variation in the rates of sequence evolution among proteins encoded by the same genome. The strongest correlate of evolutionary rate is expression level: highly expressed proteins tend to evolve slowly. This observation has led to the proposal that a major determinant of protein evolu...
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979011/ https://www.ncbi.nlm.nih.gov/pubmed/20884723 http://dx.doi.org/10.1093/gbe/evq059 |