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Expression Level, Evolutionary Rate, and the Cost of Expression

There is great variation in the rates of sequence evolution among proteins encoded by the same genome. The strongest correlate of evolutionary rate is expression level: highly expressed proteins tend to evolve slowly. This observation has led to the proposal that a major determinant of protein evolu...

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Detalles Bibliográficos
Autor principal: Cherry, Joshua L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979011/
https://www.ncbi.nlm.nih.gov/pubmed/20884723
http://dx.doi.org/10.1093/gbe/evq059

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