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2-(4-Fluorophenyl)-N-{4-[6-(4-fluorophenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]pyridin-2-yl}acetamide
In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluorophenyl and pyridine rings. The crystal structure is stabilized by intermolecular N—H⋯N hydrogen bonding and b...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979114/ https://www.ncbi.nlm.nih.gov/pubmed/21579181 http://dx.doi.org/10.1107/S1600536810012766 |
Sumario: | In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluorophenyl and pyridine rings. The crystal structure is stabilized by intermolecular N—H⋯N hydrogen bonding and by an intramolecular C—H⋯O hydrogen interaction. The F atom of the 2-(4-fluorophenyl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25. |
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