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2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide

In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro­phenyl and pyridine rings. The crystal structure is stabilized by inter­molecular N—H⋯N hydrogen bonding and b...

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Detalles Bibliográficos
Autores principales: Selig, Roland, Schollmeyer, Dieter, Albrecht, Wolfgang, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979114/
https://www.ncbi.nlm.nih.gov/pubmed/21579181
http://dx.doi.org/10.1107/S1600536810012766
Descripción
Sumario:In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro­phenyl and pyridine rings. The crystal structure is stabilized by inter­molecular N—H⋯N hydrogen bonding and by an intra­molecular C—H⋯O hydrogen inter­action. The F atom of the 2-(4-fluoro­phen­yl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25.