2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide

In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro­phenyl and pyridine rings. The crystal structure is stabilized by inter­molecular N—H⋯N hydrogen bonding and b...

Descripción completa

Detalles Bibliográficos
Autores principales: Selig, Roland, Schollmeyer, Dieter, Albrecht, Wolfgang, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979114/
https://www.ncbi.nlm.nih.gov/pubmed/21579181
http://dx.doi.org/10.1107/S1600536810012766
_version_ 1782191346678759424
author Selig, Roland
Schollmeyer, Dieter
Albrecht, Wolfgang
Laufer, Stefan
author_facet Selig, Roland
Schollmeyer, Dieter
Albrecht, Wolfgang
Laufer, Stefan
author_sort Selig, Roland
collection PubMed
description In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro­phenyl and pyridine rings. The crystal structure is stabilized by inter­molecular N—H⋯N hydrogen bonding and by an intra­molecular C—H⋯O hydrogen inter­action. The F atom of the 2-(4-fluoro­phen­yl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25.
format Text
id pubmed-2979114
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29791142010-12-30 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide Selig, Roland Schollmeyer, Dieter Albrecht, Wolfgang Laufer, Stefan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro­phenyl and pyridine rings. The crystal structure is stabilized by inter­molecular N—H⋯N hydrogen bonding and by an intra­molecular C—H⋯O hydrogen inter­action. The F atom of the 2-(4-fluoro­phen­yl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25. International Union of Crystallography 2010-04-21 /pmc/articles/PMC2979114/ /pubmed/21579181 http://dx.doi.org/10.1107/S1600536810012766 Text en © Selig et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Selig, Roland
Schollmeyer, Dieter
Albrecht, Wolfgang
Laufer, Stefan
2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title_full 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title_fullStr 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title_full_unstemmed 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title_short 2-(4-Fluoro­phen­yl)-N-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
title_sort 2-(4-fluoro­phen­yl)-n-{4-[6-(4-fluoro­phen­yl)-2,3-dihydro­imidazo[2,1-b][1,3]thia­zol-5-yl]pyridin-2-yl}acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979114/
https://www.ncbi.nlm.nih.gov/pubmed/21579181
http://dx.doi.org/10.1107/S1600536810012766
work_keys_str_mv AT seligroland 24fluorophenyln464fluorophenyl23dihydroimidazo21b13thiazol5ylpyridin2ylacetamide
AT schollmeyerdieter 24fluorophenyln464fluorophenyl23dihydroimidazo21b13thiazol5ylpyridin2ylacetamide
AT albrechtwolfgang 24fluorophenyln464fluorophenyl23dihydroimidazo21b13thiazol5ylpyridin2ylacetamide
AT lauferstefan 24fluorophenyln464fluorophenyl23dihydroimidazo21b13thiazol5ylpyridin2ylacetamide

Ejemplares similares