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4-[6,8-Dibromo-2-(2-chloro-5-nitro­phen­yl)-1,2,3,4-tetra­hydro­quinazolin-3-yl]cyclo­hexa­nol

The title compound, C(20)H(20)Br(2)ClN(3)O(3), was synthesized by the condensation reaction of 2-chloro-5-nitro­benzaldehyde with 4-(2-amino-3,5-dibromo­benzyl­amino)cyclo­hexa­nol in a methanol solution. There are two independent mol­ecules in the asymmetric unit and in one mol­ecule the atoms of t...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-Gang, Xia, Zong-Lin, Wang, Rong, Wang, Ming-Li
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979269/
https://www.ncbi.nlm.nih.gov/pubmed/21579236
http://dx.doi.org/10.1107/S1600536810015023
Descripción
Sumario:The title compound, C(20)H(20)Br(2)ClN(3)O(3), was synthesized by the condensation reaction of 2-chloro-5-nitro­benzaldehyde with 4-(2-amino-3,5-dibromo­benzyl­amino)cyclo­hexa­nol in a methanol solution. There are two independent mol­ecules in the asymmetric unit and in one mol­ecule the atoms of the cyclo­hexane ring are disordered over two sets of sites with refined occupancies of 0.657 (12) and 0.343 (12). The dihedral angle between the two benzene rings is 89.5 (2)° in one mol­ecule and 82.9 (2)° in the other. In the crystal structure, inter­molecular N—H⋯O and O—H⋯O hydrogen bonds link the mol­ecules into chains propagating along [01[Image: see text]].