19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione

In the title compound, C(32)H(26)Cl(2)N(2)O(3), the piperidone ring adopts a chair conformation and the proline and pyrrolidine rings adopt envelope conformations. The indane ring system is essentially planar with an r.m.s. deviation of 0.011 Å for the non-H atoms. The dihedral angle between the two...

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Autores principales: Kumar, Raju Suresh, Osman, Hasnah, Abdul Rahim, Aisyah Saad, Hemamalini, Madhukar, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979351/
https://www.ncbi.nlm.nih.gov/pubmed/21579517
http://dx.doi.org/10.1107/S1600536810018611
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author Kumar, Raju Suresh
Osman, Hasnah
Abdul Rahim, Aisyah Saad
Hemamalini, Madhukar
Fun, Hoong-Kun
author_facet Kumar, Raju Suresh
Osman, Hasnah
Abdul Rahim, Aisyah Saad
Hemamalini, Madhukar
Fun, Hoong-Kun
author_sort Kumar, Raju Suresh
collection PubMed
description In the title compound, C(32)H(26)Cl(2)N(2)O(3), the piperidone ring adopts a chair conformation and the proline and pyrrolidine rings adopt envelope conformations. The indane ring system is essentially planar with an r.m.s. deviation of 0.011 Å for the non-H atoms. The dihedral angle between the two chloro-substituted benzene rings is 63.69 (10)°. Intra­molecular C—H⋯O and N—H⋯O hydrogen bonds may influence the mol­ecular conformation. In the crystal structure, mol­ecules are connected into layers by weak inter­molecular C—H⋯O hydrogen bonds.
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spelling pubmed-29793512010-12-30 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione Kumar, Raju Suresh Osman, Hasnah Abdul Rahim, Aisyah Saad Hemamalini, Madhukar Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(32)H(26)Cl(2)N(2)O(3), the piperidone ring adopts a chair conformation and the proline and pyrrolidine rings adopt envelope conformations. The indane ring system is essentially planar with an r.m.s. deviation of 0.011 Å for the non-H atoms. The dihedral angle between the two chloro-substituted benzene rings is 63.69 (10)°. Intra­molecular C—H⋯O and N—H⋯O hydrogen bonds may influence the mol­ecular conformation. In the crystal structure, mol­ecules are connected into layers by weak inter­molecular C—H⋯O hydrogen bonds. International Union of Crystallography 2010-05-26 /pmc/articles/PMC2979351/ /pubmed/21579517 http://dx.doi.org/10.1107/S1600536810018611 Text en © Kumar et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Kumar, Raju Suresh
Osman, Hasnah
Abdul Rahim, Aisyah Saad
Hemamalini, Madhukar
Fun, Hoong-Kun
19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title_full 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title_fullStr 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title_full_unstemmed 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title_short 19-[(E)-4-Chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
title_sort 19-[(e)-4-chloro­benzyl­idene]-16-(4-chloro­phen­yl)-2-hydr­oxy-1,11-diaza­hexa­cyclo­[15.3.1.0(2,10).0(3,8).0(10,17).0(11,15)]henicosa-3(8),4,6-triene-9,18-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979351/
https://www.ncbi.nlm.nih.gov/pubmed/21579517
http://dx.doi.org/10.1107/S1600536810018611
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