(E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate

The title compound, C(20)H(17)N(3)O(2)·CH(4)O·H(2)O, was synthesized by the condensation reaction of 2-benzyl­oxybenzaldehyde with isoniazid (isonicotinic acid hydrazide). The tricyclic compound displays a trans configuration with respect to the C=N double bond. The central benzene ring makes dihedr...

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Autores principales: Naveenkumar, H. S., Sadikun, Amirin, Ibrahim, Pazilah, Hemamalini, Madhukar, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979361/
https://www.ncbi.nlm.nih.gov/pubmed/21579427
http://dx.doi.org/10.1107/S1600536810016958
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author Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Hemamalini, Madhukar
Fun, Hoong-Kun
author_facet Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Hemamalini, Madhukar
Fun, Hoong-Kun
author_sort Naveenkumar, H. S.
collection PubMed
description The title compound, C(20)H(17)N(3)O(2)·CH(4)O·H(2)O, was synthesized by the condensation reaction of 2-benzyl­oxybenzaldehyde with isoniazid (isonicotinic acid hydrazide). The tricyclic compound displays a trans configuration with respect to the C=N double bond. The central benzene ring makes dihedral angles of 8.83 (7) and 70.39 (8)° with the pyridine ring and the terminal benzene ring, respectively. The dihedral angle between the pyridine ring and the terminal benzene ring is 73.11 (8)°. In the crystal structure, mol­ecules are connected by inter­molecular N—H⋯O, O—H⋯O, O—H⋯(N,N) and C—H⋯O hydrogen bonds, forming a two-dimensional network perpendicular to the a axis.
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spelling pubmed-29793612010-12-30 (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate Naveenkumar, H. S. Sadikun, Amirin Ibrahim, Pazilah Hemamalini, Madhukar Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(20)H(17)N(3)O(2)·CH(4)O·H(2)O, was synthesized by the condensation reaction of 2-benzyl­oxybenzaldehyde with isoniazid (isonicotinic acid hydrazide). The tricyclic compound displays a trans configuration with respect to the C=N double bond. The central benzene ring makes dihedral angles of 8.83 (7) and 70.39 (8)° with the pyridine ring and the terminal benzene ring, respectively. The dihedral angle between the pyridine ring and the terminal benzene ring is 73.11 (8)°. In the crystal structure, mol­ecules are connected by inter­molecular N—H⋯O, O—H⋯O, O—H⋯(N,N) and C—H⋯O hydrogen bonds, forming a two-dimensional network perpendicular to the a axis. International Union of Crystallography 2010-05-15 /pmc/articles/PMC2979361/ /pubmed/21579427 http://dx.doi.org/10.1107/S1600536810016958 Text en © Naveenkumar et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Hemamalini, Madhukar
Fun, Hoong-Kun
(E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title_full (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title_fullStr (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title_full_unstemmed (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title_short (E)-N′-(2-Benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
title_sort (e)-n′-(2-benzyl­oxybenzyl­idene)isonicotinohydrazide methanol solvate monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979361/
https://www.ncbi.nlm.nih.gov/pubmed/21579427
http://dx.doi.org/10.1107/S1600536810016958
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