5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione

In the title compound, C(11)H(15)FN(2)O(5), the five-membered ring has an envelope conformation, while the six-membered ring is essentially planar, with a maximum deviation of 0.032 (2) Å from the mean plane. The crystal packing is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds, genera...

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Detalles Bibliográficos
Autores principales: Mendoza, Angel, Sosa-Rivadeneyra, Martha, Sartillo-Piscil, Fernando, Quintero, Leticia, Flores-Alamo, Marcos
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979416/
https://www.ncbi.nlm.nih.gov/pubmed/21579410
http://dx.doi.org/10.1107/S1600536810016065
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author Mendoza, Angel
Sosa-Rivadeneyra, Martha
Sartillo-Piscil, Fernando
Quintero, Leticia
Flores-Alamo, Marcos
author_facet Mendoza, Angel
Sosa-Rivadeneyra, Martha
Sartillo-Piscil, Fernando
Quintero, Leticia
Flores-Alamo, Marcos
author_sort Mendoza, Angel
collection PubMed
description In the title compound, C(11)H(15)FN(2)O(5), the five-membered ring has an envelope conformation, while the six-membered ring is essentially planar, with a maximum deviation of 0.032 (2) Å from the mean plane. The crystal packing is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds, generating a layer structure parallel to (001).
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spelling pubmed-29794162010-12-30 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione Mendoza, Angel Sosa-Rivadeneyra, Martha Sartillo-Piscil, Fernando Quintero, Leticia Flores-Alamo, Marcos Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(15)FN(2)O(5), the five-membered ring has an envelope conformation, while the six-membered ring is essentially planar, with a maximum deviation of 0.032 (2) Å from the mean plane. The crystal packing is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds, generating a layer structure parallel to (001). International Union of Crystallography 2010-05-12 /pmc/articles/PMC2979416/ /pubmed/21579410 http://dx.doi.org/10.1107/S1600536810016065 Text en © Mendoza et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mendoza, Angel
Sosa-Rivadeneyra, Martha
Sartillo-Piscil, Fernando
Quintero, Leticia
Flores-Alamo, Marcos
5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title_full 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title_fullStr 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title_full_unstemmed 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title_short 5-Fluoro-1-[(4S,5R)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1H,3H)-dione
title_sort 5-fluoro-1-[(4s,5r)-5-(2-hydroxy­ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrimidine-2,4(1h,3h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979416/
https://www.ncbi.nlm.nih.gov/pubmed/21579410
http://dx.doi.org/10.1107/S1600536810016065
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