(E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide

The title isoniazid derivative, C(16)H(17)N(3)O, exists in an E configuration with respect to the Schiff base C=N bond. The pyridine ring is essentially planar [maximum deviation = 0.009 (3) Å]. The mean plane through the hydrazide unit forms dihedral angles of 38.38 (16) and 39.42 (16)°, respective...

Descripción completa

Detalles Bibliográficos
Autores principales: Naveenkumar, H. S., Sadikun, Amirin, Ibrahim, Pazilah, Goh, Jia Hao, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979577/
https://www.ncbi.nlm.nih.gov/pubmed/21579555
http://dx.doi.org/10.1107/S1600536810019446
_version_ 1782191446344859648
author Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Goh, Jia Hao
Fun, Hoong-Kun
author_facet Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Goh, Jia Hao
Fun, Hoong-Kun
author_sort Naveenkumar, H. S.
collection PubMed
description The title isoniazid derivative, C(16)H(17)N(3)O, exists in an E configuration with respect to the Schiff base C=N bond. The pyridine ring is essentially planar [maximum deviation = 0.009 (3) Å]. The mean plane through the hydrazide unit forms dihedral angles of 38.38 (16) and 39.42 (16)°, respectively, with the pyridine and benzene rings. In the crystal structure, symmetry-related mol­ecules are linked via inter­molecular N—H⋯O hydrogen bonds into chains along [100]. The crystal structure is further stabilized by weak inter­molecular C—H⋯π inter­actions.
format Text
id pubmed-2979577
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29795772010-12-30 (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide Naveenkumar, H. S. Sadikun, Amirin Ibrahim, Pazilah Goh, Jia Hao Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The title isoniazid derivative, C(16)H(17)N(3)O, exists in an E configuration with respect to the Schiff base C=N bond. The pyridine ring is essentially planar [maximum deviation = 0.009 (3) Å]. The mean plane through the hydrazide unit forms dihedral angles of 38.38 (16) and 39.42 (16)°, respectively, with the pyridine and benzene rings. In the crystal structure, symmetry-related mol­ecules are linked via inter­molecular N—H⋯O hydrogen bonds into chains along [100]. The crystal structure is further stabilized by weak inter­molecular C—H⋯π inter­actions. International Union of Crystallography 2010-05-29 /pmc/articles/PMC2979577/ /pubmed/21579555 http://dx.doi.org/10.1107/S1600536810019446 Text en © Naveenkumar et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Naveenkumar, H. S.
Sadikun, Amirin
Ibrahim, Pazilah
Goh, Jia Hao
Fun, Hoong-Kun
(E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title_full (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title_fullStr (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title_full_unstemmed (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title_short (E)-N′-(2,4,6-Trimethyl­benzyl­idene)isonicotinohydrazide
title_sort (e)-n′-(2,4,6-trimethyl­benzyl­idene)isonicotinohydrazide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979577/
https://www.ncbi.nlm.nih.gov/pubmed/21579555
http://dx.doi.org/10.1107/S1600536810019446
work_keys_str_mv AT naveenkumarhs en246trimethylbenzylideneisonicotinohydrazide
AT sadikunamirin en246trimethylbenzylideneisonicotinohydrazide
AT ibrahimpazilah en246trimethylbenzylideneisonicotinohydrazide
AT gohjiahao en246trimethylbenzylideneisonicotinohydrazide
AT funhoongkun en246trimethylbenzylideneisonicotinohydrazide

Ejemplares similares