Redetermination and absolute configuration of atalaphylline

The title acridone alkaloid [systematic name: 1,3,5-trihydr­oxy-2,4-bis­(3-methyl­but-2-en­yl)acridin-9(10H)-one], C(23)H(25)NO(4), has previously been reported as crystallizing in the chiral ortho­rhom­bic space group P2(1)2(1)2(1) [Chantrapromma et al. (2010 ▶). Acta Cryst. E66, o81–o82] but the a...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Yeap, Chin Sing, Chantrapromma, Suchada
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979734/
https://www.ncbi.nlm.nih.gov/pubmed/21579697
http://dx.doi.org/10.1107/S160053680905449X
Descripción
Sumario:The title acridone alkaloid [systematic name: 1,3,5-trihydr­oxy-2,4-bis­(3-methyl­but-2-en­yl)acridin-9(10H)-one], C(23)H(25)NO(4), has previously been reported as crystallizing in the chiral ortho­rhom­bic space group P2(1)2(1)2(1) [Chantrapromma et al. (2010 ▶). Acta Cryst. E66, o81–o82] but the absolute configuration could not be determined from data collected with Mo radiation. The absolute configuration has now been determined by refinement of the Flack parameter with data collected using Cu radiation. All features of the mol­ecule and its crystal packing are similar to those previously described.

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