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N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine

The title compound, C(16)H(15)N(5), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in mol­ecule A, and 6.8 (1) and 11.6 (9)° in mol­ecule B. The cry...

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Autores principales: Jasinski, Jerry P., Butcher, Ray J., Hakim Al-Arique, Q. N. M., Yathirajan, H. S., Narayana, B.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979750/
https://www.ncbi.nlm.nih.gov/pubmed/21579776
http://dx.doi.org/10.1107/S1600536810000899
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author Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-Arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
author_facet Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-Arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
author_sort Jasinski, Jerry P.
collection PubMed
description The title compound, C(16)H(15)N(5), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in mol­ecule A, and 6.8 (1) and 11.6 (9)° in mol­ecule B. The crystal packing is influenced by the collective action of weak inter­molecular N—H⋯N hydrogen bonds, a π–π stacking inter­action between neighbouring pyridyl rings of mol­ecule A [centroid–centroid distance = 3.8395 (10) Å] and C—H⋯π inter­actions.
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spelling pubmed-29797502010-12-30 N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine Jasinski, Jerry P. Butcher, Ray J. Hakim Al-Arique, Q. N. M. Yathirajan, H. S. Narayana, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(16)H(15)N(5), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in mol­ecule A, and 6.8 (1) and 11.6 (9)° in mol­ecule B. The crystal packing is influenced by the collective action of weak inter­molecular N—H⋯N hydrogen bonds, a π–π stacking inter­action between neighbouring pyridyl rings of mol­ecule A [centroid–centroid distance = 3.8395 (10) Å] and C—H⋯π inter­actions. International Union of Crystallography 2010-01-13 /pmc/articles/PMC2979750/ /pubmed/21579776 http://dx.doi.org/10.1107/S1600536810000899 Text en © Jasinski et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-Arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title_full N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title_fullStr N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title_full_unstemmed N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title_short N-(5-Amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
title_sort n-(5-amino-2-methyl­phen­yl)-4-(3-pyri­dyl)­pyrimidin-2-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979750/
https://www.ncbi.nlm.nih.gov/pubmed/21579776
http://dx.doi.org/10.1107/S1600536810000899
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