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N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine
The title compound, C(16)H(15)N(5), crystallizes with two independent molecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in molecule A, and 6.8 (1) and 11.6 (9)° in molecule B. The cry...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979750/ https://www.ncbi.nlm.nih.gov/pubmed/21579776 http://dx.doi.org/10.1107/S1600536810000899 |
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author | Jasinski, Jerry P. Butcher, Ray J. Hakim Al-Arique, Q. N. M. Yathirajan, H. S. Narayana, B. |
author_facet | Jasinski, Jerry P. Butcher, Ray J. Hakim Al-Arique, Q. N. M. Yathirajan, H. S. Narayana, B. |
author_sort | Jasinski, Jerry P. |
collection | PubMed |
description | The title compound, C(16)H(15)N(5), crystallizes with two independent molecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in molecule A, and 6.8 (1) and 11.6 (9)° in molecule B. The crystal packing is influenced by the collective action of weak intermolecular N—H⋯N hydrogen bonds, a π–π stacking interaction between neighbouring pyridyl rings of molecule A [centroid–centroid distance = 3.8395 (10) Å] and C—H⋯π interactions. |
format | Text |
id | pubmed-2979750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29797502010-12-30 N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine Jasinski, Jerry P. Butcher, Ray J. Hakim Al-Arique, Q. N. M. Yathirajan, H. S. Narayana, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(16)H(15)N(5), crystallizes with two independent molecules (A and B) in the asymmetric unit. The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in molecule A, and 6.8 (1) and 11.6 (9)° in molecule B. The crystal packing is influenced by the collective action of weak intermolecular N—H⋯N hydrogen bonds, a π–π stacking interaction between neighbouring pyridyl rings of molecule A [centroid–centroid distance = 3.8395 (10) Å] and C—H⋯π interactions. International Union of Crystallography 2010-01-13 /pmc/articles/PMC2979750/ /pubmed/21579776 http://dx.doi.org/10.1107/S1600536810000899 Text en © Jasinski et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Jasinski, Jerry P. Butcher, Ray J. Hakim Al-Arique, Q. N. M. Yathirajan, H. S. Narayana, B. N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title_full |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title_fullStr |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title_full_unstemmed |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title_short |
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
title_sort | n-(5-amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979750/ https://www.ncbi.nlm.nih.gov/pubmed/21579776 http://dx.doi.org/10.1107/S1600536810000899 |
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