(3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione

In the title compound, C(9)H(14)N(2)O(2), the pyrrolidine and piperazine rings adopt envelope and boat conformations, respectively. The chiral centers were assigned on the basis of the known stereogenic center of an enanti­omerically pure starting material and the trans relationship between the H at...

Descripción completa

Detalles Bibliográficos
Autores principales: Bortoluzzi, Adailton J., Souza, Luciana B. P., Joussef, Antonio C.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979809/
https://www.ncbi.nlm.nih.gov/pubmed/21579835
http://dx.doi.org/10.1107/S1600536810001856
_version_ 1782191506672582656
author Bortoluzzi, Adailton J.
Souza, Luciana B. P.
Joussef, Antonio C.
author_facet Bortoluzzi, Adailton J.
Souza, Luciana B. P.
Joussef, Antonio C.
author_sort Bortoluzzi, Adailton J.
collection PubMed
description In the title compound, C(9)H(14)N(2)O(2), the pyrrolidine and piperazine rings adopt envelope and boat conformations, respectively. The chiral centers were assigned on the basis of the known stereogenic center of an enanti­omerically pure starting material and the trans relationship between the H atoms attached to these centers. The crystal packing is stabilized by an inter­molecular hydrogen bond between the N—H group and a carbonyl O atom of the diketopiperazine group, forming zigzag C(5) chains along [010].
format Text
id pubmed-2979809
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29798092010-12-30 (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione Bortoluzzi, Adailton J. Souza, Luciana B. P. Joussef, Antonio C. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(9)H(14)N(2)O(2), the pyrrolidine and piperazine rings adopt envelope and boat conformations, respectively. The chiral centers were assigned on the basis of the known stereogenic center of an enanti­omerically pure starting material and the trans relationship between the H atoms attached to these centers. The crystal packing is stabilized by an inter­molecular hydrogen bond between the N—H group and a carbonyl O atom of the diketopiperazine group, forming zigzag C(5) chains along [010]. International Union of Crystallography 2010-01-23 /pmc/articles/PMC2979809/ /pubmed/21579835 http://dx.doi.org/10.1107/S1600536810001856 Text en © Bortoluzzi et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Bortoluzzi, Adailton J.
Souza, Luciana B. P.
Joussef, Antonio C.
(3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title_full (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title_fullStr (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title_full_unstemmed (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title_short (3R,8aS)-3-Ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
title_sort (3r,8as)-3-ethyl­perhydro­pyrrolo[1,2-a]pyrazine-1,4-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979809/
https://www.ncbi.nlm.nih.gov/pubmed/21579835
http://dx.doi.org/10.1107/S1600536810001856
work_keys_str_mv AT bortoluzziadailtonj 3r8as3ethylperhydropyrrolo12apyrazine14dione
AT souzalucianabp 3r8as3ethylperhydropyrrolo12apyrazine14dione
AT joussefantonioc 3r8as3ethylperhydropyrrolo12apyrazine14dione

Ejemplares similares