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6-Fluoro-4-oxochroman-2-carboxylic acid

The title compound, C(10)H(7)FO(4), is an intermediate in the synthesis of the drug Fidarestat, (2S,4S)-2-aminoformyl-6-fluoro-spiro[chroman-4,4′-imidazolidine]-2′,5′-dione. The dihydropyranone ring adopts an envelope conformation with the asymmetric C atom in the flap position. In the crystal,...

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Detalles Bibliográficos
Autores principales:	Chen, Pei, Qian, Shan, Shi, Zhe-Qin, Wu, Yong
Formato:	Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2010
Materias:	Organic Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979877/ https://www.ncbi.nlm.nih.gov/pubmed/21579711 http://dx.doi.org/10.1107/S1600536809054555

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