Cargando…

1,2-Dihydr­oxy-2-(3-methyl­but-2-en­yl)-3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid monohydrate

The title compound, C(15)H(16)O(5)·H(2)O, is an inter­mediate of the Hooker oxidation reaction, used for the synthesis of 2-hydr­oxy-3-(2-methyl­prop-1-en­yl)naphthalene-1,4-dione (nor-lapachol). The packing in the crystal structure is arranged by an O—H⋯O hydrogen-bonded network along the [100] and...

Descripción completa

Detalles Bibliográficos
Autores principales: Franscisco, Acácio Ivo, de Q. Silveira, Gleiciani, Resende, Jackson A. L. C., Balliano, Tatiane L., Malta, Valéria R. S., Pinto, Antonio Ventura
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979928/
https://www.ncbi.nlm.nih.gov/pubmed/21579770
http://dx.doi.org/10.1107/S1600536810000516
Descripción
Sumario:The title compound, C(15)H(16)O(5)·H(2)O, is an inter­mediate of the Hooker oxidation reaction, used for the synthesis of 2-hydr­oxy-3-(2-methyl­prop-1-en­yl)naphthalene-1,4-dione (nor-lapachol). The packing in the crystal structure is arranged by an O—H⋯O hydrogen-bonded network along the [100] and [010] directions. Each organic mol­ecule is linked to four other mol­ecules via the hydr­oxy groups. The water solvent mol­ecule is connected to carboxylic acid groups by three hydrogen bonds.