N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate

In the crystal structure of the title compound, C(18)H(17)FN(4)O(2)S·2H(2)O, the organic mol­ecules are linked by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds with the water mol­ecules, generating a three-dimensional network. The imidazole ring system forms a dihedral angle of 24.9 (2)° wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Bühler, Stefanie, Schollmeyer, Dieter, Hauser, Dominik, Albrecht, Wolfgang, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980079/
https://www.ncbi.nlm.nih.gov/pubmed/21580011
http://dx.doi.org/10.1107/S1600536809051873
Descripción
Sumario:In the crystal structure of the title compound, C(18)H(17)FN(4)O(2)S·2H(2)O, the organic mol­ecules are linked by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds with the water mol­ecules, generating a three-dimensional network. The imidazole ring system forms a dihedral angle of 24.9 (2)° with the 4-fluoro­phenyl ring. The pyridine ring is oriented approximately perpendicular [72.24 (8)°] to the imidazole ring system.

Ejemplares similares